7713-83-9

Basic information

• Product Name: Thiourea, [4-(4-methoxyphenyl)-2-thiazolyl]-
• CAS NO: 7713-83-9
• Molecular Formula: C11H11N3OS2
• Molecular Weight: 265.36
• Mol File: 7713-83-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Thiourea, [4-(4-methoxyphenyl)-2-thiazolyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, [4-(4-methoxyphenyl)-2-thiazolyl]-(7713-83-9)
• EPA Substance Registry System: Thiourea, [4-(4-methoxyphenyl)-2-thiazolyl]-(7713-83-9)

Safety Data

• Hazardous Substances Data: 7713-83-9(Hazardous Substances Data)

Upstream product

• 2104-04-3 4-(4-methoxyphenyl)-1,3-thiazol-2-amine 
• 1147550-11-5 ammonium thiocyanate 
• 541-53-7 2,4-Dithiobiuret 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 89402-64-2 N-(4-p-methoxyphenyl-2-thiazolyl)-N'-benzoylthiourea 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 52471-15-5 5-bromo-5-[bromo-(2-nitro-phenyl)-methyl]-2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-thiazol-4-one 
• 52414-45-6 5-bromo-5-[bromo-(4-nitro-phenyl)-methyl]-3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-thioxo-imidazolidin-4-one 
• 52414-46-7 5-bromo-5-[bromo-(2-nitro-phenyl)-methyl]-3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-thioxo-imidazolidin-4-one 
• 52414-10-5 5-bromo-5-[bromo-(4-nitro-phenyl)-methyl]-2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-thiazol-4-one 
• 52414-44-5 5-bromo-5-[bromo-(4-methoxy-phenyl)-methyl]-3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-thioxo-imidazolidin-4-one 
• 52414-11-6 5-bromo-5-[bromo-(4-methoxy-phenyl)-methyl]-2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-thiazol-4-one 
• 52414-47-8 5-bromo-5-[bromo-(2-chloro-phenyl)-methyl]-3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-thioxo-imidazolidin-4-one 
• 52471-16-6 5-bromo-5-[bromo-(2-chloro-phenyl)-methyl]-2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-thiazol-4-one 
• 52414-43-4 5-bromo-5-(bromo-phenyl-methyl)-3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-thioxo-imidazolidin-4-one 
• 52414-09-2 5-bromo-5-(bromo-phenyl-methyl)-2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-thiazol-4-one 
• 52414-29-6 3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-5-(4-nitro-benzylidene)-2-thioxo-imidazolidin-4-one 
• 52414-30-9 3-[4-(4-methoxy-phenyl)-thiazol-2-yl]-5-(2-nitro-benzylidene)-2-thioxo-imidazolidin-4-one 
• 52413-98-6 2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-5-(2-nitro-benzylidene)-thiazol-4-one 
• 52413-97-5 2-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-5-(4-nitro-benzylidene)-thiazol-4-one 

Relevant articles and documents

Synthesis and biological evaluation of substituted thiazolamine, imidazo [2,1-b] thiazol-6(5H)-one, thiazolo [3,2-a] pyrimidin-5-one and thiazolyl thiourea derivatives

Substituted phenyl thiazole-2-amines (TA1-4) refluxed with ethyl acetoacetate using phosphorus oxychloride and polyphosphoric acid as a catalyst yielded thiazolo- pyrimidines (TP1-4) and with chloroacetic acid in ethanol furnished imizado- Thiazolos (IT1-4). Thiazolyl thioreas (TT1-4) were synthesized by the reaction of TA1-4 with ammonium thiocynate in dil hydrochloric acid. The structures of the synthesized compounds have been established on the basis of their spectral data and drug likelines was analyzed using Molinspiration online resource. The in vitro tuberculostatic potential evaluated against H37Rv strain of Mycobacterium tuberculosis by REMA assay has shown moderate activity for compound IT2. Synthesized compounds were screened against Staphylococcus aureus (MTCC 3160), Bacillus subtilis (MTCC 441), Escherichia coli (MTCC 40) and Pseudomonus aeruginosa (MTCC 424) bacteria and have shown significant activity.

SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF SOME 2,2'-IMINOBISTHIAZOLES

-