77140-20-6

Basic information

• Product Name: 5,5-dimethyl-4-benzyloxy-[5H]furan-2-one
• CAS NO: 77140-20-6
• Molecular Weight: 218.252
• Mol File: 77140-20-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,5-dimethyl-4-benzyloxy-[5H]furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-4-benzyloxy-[5H]furan-2-one(77140-20-6)
• EPA Substance Registry System: 5,5-dimethyl-4-benzyloxy-[5H]furan-2-one(77140-20-6)

Safety Data

• Hazardous Substances Data: 77140-20-6(Hazardous Substances Data)

Upstream product

• 19444-23-6 benzyl 2-hydroxy-2-methylpropanoate 
• 73818-55-0 Bestmann ylide 
• 22621-30-3 4-hydroxy-5,5-dimethyl-5H-furan-2-one 
• 100-51-6 benzyl alcohol 

Downstream Products

• 22621-30-3 4-hydroxy-5,5-dimethyl-5H-furan-2-one 

Relevant articles and documents

Tipranavir analogous 3-sulfonylanilidotetronic acids: new synthesis and structure-dependent anti-HIV activity

Sulfonamide-containing tetronic acids 1, structural analogues of the HIV-1 protease inhibitor tipranavir, were synthesised in five steps including a microwave-assisted Claisen rearrangement of cinnamyl tetronates and a modified Charette cyclopropanation of the so-formed 3-allyltetronic acids. Compounds 1 with two non-H residues (R1, R2) at C-5 of the tetronate core exhibited structure-dependent antiviral activity in two HIV strains. Derivatives 1c (R1=R2=Me, R3=Cl) and 1d (R1,2=(CH2)5, R3=Me) were most active (IC50NL4-3.