77150-73-3

Upstream product

• 80403-45-8 (2S,5R)-4,4-Dimethyl-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 77150-72-2 [2-(1,1-Dimethyl-2-oxo-ethyl)-4-oxo-azetidin-1-yl]-acetic acid benzyl ester 
• 80403-42-5 2-(1-Benzyloxycarbonylmethyl-4-oxo-azetidin-2-yl)-2-methyl-propionic acid 
• 80403-44-7 [2-(1-Chlorocarbonyl-1-methyl-ethyl)-4-oxo-azetidin-1-yl]-acetic acid benzyl ester 
• 5437-45-6 Benzyl bromoacetate 
• 77150-71-1 [2-(1,1-Dimethyl-allyl)-4-oxo-azetidin-1-yl]-acetic acid benzyl ester 
• 74949-60-3 4-(1,1-dimethyl-prop-2-enyl)-azetidin-2-one 

Downstream Products

• 77150-74-4 (2R,3S,5S)-4,4-Dimethyl-7-oxo-3-trimethylsilanyloxy-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 77150-70-0 4,4-Dimethyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid benzyl ester 
• 80403-49-2 (3R,5S)-3-Hydroxy-4,4-dimethyl-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid; compound with 2,2,4a,7,7-pentamethyl-1,2,3,4,4a,5,6,7-octahydro-[1,8]naphthyridine 
• 77150-75-5 (2S,3S,5R)-3-Methanesulfonyloxy-4,4-dimethyl-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 77150-75-5 (2R,3S,5S)-3-Methanesulfonyloxy-4,4-dimethyl-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF 1,1-DIMETHYLCARBA-2-PENEM DERIVATIVES VIA A DIECKMANN-TYPE CYCLIZATION

The synthesis of 1,1-dimethylcarba-2-penem derivatives via a Dieckmann-type cyclization and the use of a new method for removing the benzyl protecting group are reported.

SYNTHESIS OF 1,1-DIMETHYLCARBAPEN-2-EM DERIVATIVE VIA AN ALDOL-TYPE CYCLIZATION

The synthesis of 1,1-dimethylcarbapen-2-em derivative 3 is described.The key step in the synthesis is an intramolecular aldol-type condensation reaction.