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771572-85-1

C-(2-Chloro-6-trifluoroMethyl-pyridin-3-yl)-MethylaMine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

771572-85-1

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771572-85-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 771572-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,1,5,7 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 771572-85:
(8*7)+(7*7)+(6*1)+(5*5)+(4*7)+(3*2)+(2*8)+(1*5)=191
191 % 10 = 1
So 771572-85-1 is a valid CAS Registry Number.

771572-85-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-chloro-6-(trifluoromethyl)pyridin-3-yl]methanamine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:771572-85-1 SDS

771572-85-1Relevant articles and documents

2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists

Ryu, Hyungchul,Seo, Sejin,Cho, Seong-Hee,Kim, Ho Shin,Jung, Aeran,Kang, Dong Wook,Son, Karam,Cui, Minghua,Hong, Sun-Hye,Sharma, Pankaz Kumar,Choi, Sun,Blumberg, Peter M.,Frank-Foltyn, Robert,Bahrenberg, Gregor,Stockhausen, Hannelore,Schiene, Klaus,Christoph, Thomas,Frormann, Sven,Lee, Jeewoo

, p. 4039 - 4043 (2014/09/16)

A series of 2-alkyl/alkenyl pyridine C-region derivatives of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides were investigated as hTRPV1 antagonists. Multiple compounds showed excellent and stereospecific TRPV1 antagonism with better potency than previous lead 2. Among them, compound 15f demonstrated a strong analgesic profile in a rat neuropathic pain model and blocked capsaicin-induced hypothermia in a dose-dependent manner. Docking analysis of (S)-15f with our hTRPV1 homology model provided insight into its specific binding mode.

2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4- methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists

Ryu, Hyungchul,Seo, Sejin,Kim, Myeong Seop,Kim, Mi-Yeon,Kim, Ho Shin,Ann, Jihyae,Tran, Phuong-Thao,Hoang, Van-Hai,Byun, Jieun,Cui, Minghua,Son, Karam,Sharma, Pankaz Kumar,Choi, Sun,Blumberg, Peter M.,Frank-Foltyn, Robert,Bahrenberg, Gregor,Koegel, Babette-Yvonne,Christoph, Thomas,Frormann, Sven,Lee, Jeewoo

, p. 4044 - 4047 (2014/09/03)

A series of 2-aryl pyridine C-region derivatives of 2-(3-fluoro-4- methylsulfonylaminophenyl)propanamides were investigated as hTRPV1 antagonists. Multiple compounds showed highly potent TRPV1 antagonism toward capsaicin comparable to previous lead 7. Among them, compound 9 demonstrated anti-allodynia in a mouse neuropathic pain model and blocked capsaicin-induced hypothermia in a dose-dependent manner. Docking analysis of 9 with our hTRPV1 homology model provided insight into its specific binding mode.

Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands

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Paragraph 0265; 0269, (2013/04/10)

The invention relates to substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseas

SUBSTITUTED METHANESULFONAMIDE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

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Page/Page column 40, (2013/04/13)

The invention relates to substituted methanesulfonamide derivatives as vanilloid receptor ligands of formula (I), to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and

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