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771579-27-2

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771579-27-2 Usage

General Description

2(1H)-Pyridinone, 3-(aminomethyl)-4,6-dimethyl- (9CI) is a chemical compound with the molecular formula C9H11N3O. It is a derivative of pyridine and is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active compounds. This chemical is known for its antimicrobial, antifungal, and anti-inflammatory properties. It may also have potential applications in the development of new therapeutic agents for the treatment of various diseases and conditions. Additionally, it is important to handle this chemical with caution as it may pose health risks if not used properly and in accordance with safety regulations.

Check Digit Verification of cas no

The CAS Registry Mumber 771579-27-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,1,5,7 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 771579-27:
(8*7)+(7*7)+(6*1)+(5*5)+(4*7)+(3*9)+(2*2)+(1*7)=202
202 % 10 = 2
So 771579-27-2 is a valid CAS Registry Number.

771579-27-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(aminomethyl)-4,6-dimethyl-1H-pyridin-2-one

1.2 Other means of identification

Product number -
Other names HMS1741L20

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:771579-27-2 SDS

771579-27-2Downstream Products

771579-27-2Relevant articles and documents

Small molecule compound based on EZH2 protein degradation, and application thereof

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Paragraph 0031-0034; 0040, (2021/08/07)

The invention discloses a series of small molecule compounds capable of selectively degrading EZH2 protein, and application thereof. The compounds can be prepared into proper pharmaceutical dosage forms for EZH2-mediated related tumor treatment.

Discovery of quinolone derivatives as antimycobacterial agents

Gao, Chao,Li, Xiao,Liu, Kun-Lin,Teng, Fei,Xiong, Lu,Yu, Luo-Ting

, p. 24095 - 24115 (2021/07/29)

Tuberculosis (TB), an infectious disease caused byMycobacterium tuberculosis(M. tuberculosis), is an important public health issue. Current first-line drugs administered to TB patients have been in use for over 40 years, whereas second-line drugs display strong side effects and poor compliance. Additionally, designing effective regimens to treat patients infected with multi- and extremely-drug-resistant (MDR and XDR) strains of TB is challenging. In this report, we screened our compound library and identified compound1with antituberculosis activity and a minimal inhibitory concentration (MIC) againstM. tuberculosisof 20 μg mL?1. Structure optimization and the structure-activity relationship of1as the lead compound enabled the design and synthesis of a series of quinolone derivatives,6a1-6a2,6b1-6b36,6c1,6d1-6d14,7a1-7a2,7b1-7b2,7c1,8a1-8a5,9a1-9a4and10a1-10a6. These compounds were evaluatedin vitrofor anti-tubercular activity against theM. tuberculosisH37Rv strain. Among them, compounds6b6,6b12and6b21exhibited MIC values in the range of 1.2-3 μg mL?1and showed excellent activity against the tested MDR-TB strain (MIC: 3, 2.9 and 0.9 μg mL?1, respectively). All three compounds were non-toxic toward A549 and Vero cells (>100 and >50 μg mL?1, respectively). In addition, an antibacterial spectrum test carried out using compound6b21showed that this compound specifically inhibitsM. tuberculosis. These can serve as a new starting point for the development of anti-TB agents with therapeutic potential.

1,5,7-TRISUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES

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Paragraph 0150-0152, (2020/08/30)

The present disclosure relates to 1,5,7-trisubstituted isoquinoline derivatives, their preparation and pharmaceutical use. In particular, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof. The definitions of the groups in the formula can be found in the specification and claims.

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