7716-87-2

Usage

Uses

Used in Pharmaceutical Industry:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as an intermediate for the synthesis of various pharmaceuticals, leveraging its reactivity and structural properties to create a range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, (5-Chloro-2-nitrophenyl)phenylmethanone is utilized as a building block for the development of different agrochemicals, contributing to its role in the production of substances that protect crops and enhance agricultural productivity.
Used as an Anti-inflammatory Agent:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as an anti-inflammatory agent, where its potential to alleviate inflammation is harnessed for therapeutic purposes.
Used as an Antipyretic Agent:
(5-Chloro-2-nitrophenyl)phenylmethanone is also employed as an antipyretic agent, helping to reduce fever and associated symptoms in patients.
Used in Organic Synthesis:
(5-Chloro-2-nitrophenyl)phenylmethanone is used as a building block in organic synthesis, where its reactivity, particularly due to the nitro group, is exploited in various chemical reactions such as nucleophilic aromatic substitution and reduction reactions, leading to the creation of a diverse array of organic compounds.

Upstream product

• 24400-58-6 6-chloro-3-phenyl-2,1-benzisoxazole 

Downstream Products

• 146470-15-7 C₁₄H₁₂ClN₅O₂*ClH 
• 64133-88-6 2-(3-Benzoyl-4-nitro-phenyl)-2-phenyl-butyronitrile 
• 64133-87-5 2-(3-Benzoyl-4-nitro-phenyl)-2-phenyl-propionitrile 
• 42872-30-0 alpha-(m-benzoylphenyl)propionitrile 
• 22071-15-4 ketoprofen 
• 64133-82-0 2.5-Dibenzoyl-4-chloranilin 
• 64133-90-0 (5-chloro-3-phenyl-benzo[c]isoxazol-7-yl)-phenyl-methanone 
• 62597-53-9 2,2'-Dibenzoyl-4,4'-dichlor-azoxybenzol 
• 719-64-2 5-chloro-3-phenylanthranil 

Relevant academic research and scientific papers

Ketoprofen intermediate as well as preparation method and application thereof

The invention relates to the field, of medicine synthesis, in particular to a ketoprofen intermediate and a preparation method and application. thereof to prepare the ketoprofen, reaction formula by sequentially performing an oxidation reaction, substitution reaction, deamination, deamination and an acidic hydrolysis reaction after formation of the isoxazole compound, by a Diels,Alder reaction with a phenylacetic acid by. a Diels :Alder reaction of a phenylacetic acid. In-flight, X2 or. Ortho or para, R to nitro or amino group1 - COCONR4 R5 , COX1 , COOR2 Or - CNCNCNR2 , R3 , R4 , R5 , R6 The same or different is H or C. 1 - C6 Alkyl, X1 , X2 The same or different is F, Cl, Br or I.

Ketoprofen intermediate as well as preparation method and application thereof

The invention relates to the field of medicine synthesis, in particular to a Ketoprofen intermediate as well as a preparation method and application thereof. Ketoprofen is prepared from p--nitrohalobenzene and o-nitrohalobenzene or a mixture of the p-nitrohalobenzene and the o-nitrohalobenzene as raw materials by first performing Diels-Alder reaction on the raw materials and phenylacetonitrile toobtain an isoxazole compound, and then sequentially carrying out oxidation reaction, substitution reaction, reduction reaction, deamination, ester removal and acid hydrolysis reaction to prepare the ketoprofen. The reaction formula is as shown in the specification, wherein X2 and a group as shown in the specification are located in ortho-position or para-position of a nitro group or an amino group, R1 is-CONR4R5,-COX1,-COOR2 or-CN, R2, R3, R4 and R5 are same or differently H or a C1-C6 alkyl group, and X1 and X2 are the same or different, and are F, Cl, Br Or I.