77178-40-6Relevant articles and documents
PTERIDINES, LXX - SYNTHESIS AND PROPERTIES OF 1,8-ALKYLENE-BRIDGED LUMAZINES
Uhlmann, Eugen,Pfleiderer, Wolfgang
, p. 437 - 453 (2007/10/02)
A new type of lumazine derivatives (24-30) with a 1,8-alkylene bridge has been synthesized to study the protonation site in lumazine (1) itself.Comparisons of UV-data, however, do not allow a clear decision in this respect but indicate possibly the presence of a mixture of at least two cationic species.The structures of the newly synthesized compounds have been proven by UV- and NMR-spectra as well as pKa measurements and elementary analyses. 8-β-Hydroxyethyl-7-oxo-7,8-dihydrolumazines (15-17) show an easy cyclization to the corresponding 1,8-ethano-bridged derivatives 18-20 on boiling with DMF.