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5-Fluorouridine, a synthetic analog of the nucleoside uridine, is distinguished by the presence of a fluorine atom at the 5-position. It is recognized for its potential as an anticancer agent, with the capacity to inhibit RNA synthesis and interfere with nucleic acid metabolism. 5-Fluorouridine has demonstrated antitumor activity and is a subject of research for its applicability in treating a range of cancers. Moreover, 5-Fluorouridine serves as a valuable biochemical tool for investigating RNA function and metabolism. Its potential as a radiosensitizer, which could amplify the impact of radiotherapy in cancer treatment, is also being explored. While its clinical application is promising, ongoing studies are essential to elucidate its mechanisms and therapeutic potential fully.

77180-80-4

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77180-80-4 Usage

Uses

Used in Pharmaceutical Research:
5-Fluorouridine is used as a potential anticancer agent for its ability to inhibit RNA synthesis and disrupt nucleic acid metabolism, which contributes to its antitumor activity.
Used in Cancer Treatment:
5-Fluorouridine is used as a therapeutic agent for the treatment of various types of cancer, given its demonstrated efficacy in inhibiting tumor growth.
Used in Biochemical Research:
5-Fluorouridine is utilized as a biochemical tool for studying the function and metabolism of RNA, providing insights into the fundamental processes of gene expression and regulation.
Used in Radiotherapy Enhancement:
5-Fluorouridine is used as a radiosensitizer to improve the effectiveness of radiotherapy in cancer treatment, potentially making it a valuable adjunct in cancer management strategies.
Used in Clinical Investigation:
5-Fluorouridine is under investigation for its clinical applications, with ongoing research aimed at understanding its mechanisms of action and exploring its full therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 77180-80-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77180-80:
(7*7)+(6*7)+(5*1)+(4*8)+(3*0)+(2*8)+(1*0)=144
144 % 10 = 4
So 77180-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m0/s1

77180-80-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Fluorouridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77180-80-4 SDS

77180-80-4Downstream Products

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