77186-41-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile is used as a chemical intermediate for the synthesis of various drugs and other biologically active compounds. Its unique structure allows it to be a key component in the development of new pharmaceuticals.
Used in Research:
In the field of research, 2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile is used as a reagent in organic synthesis. Its properties make it a valuable tool for scientists working on the development of new organic compounds and materials.
Safety Precautions:
Due to its hazardous nature, 2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile requires proper safety precautions during handling and storage. It is essential to follow guidelines and regulations to ensure the safety of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 77186-41-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,8 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 77186-41:
(7*7)+(6*7)+(5*1)+(4*8)+(3*6)+(2*4)+(1*1)=155
155 % 10 = 5
So 77186-41-5 is a valid CAS Registry Number.
77186-41-5Relevant academic research and scientific papers
New 2,3-substituted 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a]pyrimidin-7-ones and related compounds: Synthesis and benzodiazepine receptor binding study
Selleri,Bruni,Costanzo,Guerrini,Casilli,Giusti,Lucacchini,Martini
, p. 679 - 687 (2007/10/03)
The reaction between two series of 7-dimethylaminovinyl pyrazolo[1,5-a]pyrimidines 4(a-r) 7a, 7d, 7f, 7(h-j) and hydrazine in acetic acid is investigated. The structure of 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a]pyrimidin-7-ones 5(a-r) and 7-methyl-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5a]pyrimidines 8a, 8d, 8f, 8(h-j) are attributed to the isolated products and the pathway of this reaction is suggested. The in vitro benzodiazepine receptor (BzR) affinity of the title compounds are determined by testing their ability to displace 3H-flunitrazepam from its specific binding in bovine brain membranes. The IC50 and GABA (γ-aminobutyric acid) ratio values give valuable indications about affinity and behavioural profile of these new BzR ligands. Included in this investigation are indicated several structure affinity relationships of the title compounds.
