77196-89-5 Usage
Type of compound
Synthetic organic compound
Structural features
Derivative of thiadiazole
Contains a carboxamide group
Contains a hydroxyl group on the N and 4-methyl positions
Potential applications
Medicinal chemistry
Pharmaceutical development
Bioactivity
N-hydroxy group can form reactive oxygen species
Thiadiazole core has pharmacological activities
Pharmacological activities
Anti-cancer
Anti-inflammatory
Anti-microbial
Further research needed
To explore potential therapeutic applications and biological activities
Please note that this list is based on the provided material and may not be exhaustive. Additional research and information may reveal more properties and applications for 1,2,3-Thiadiazole-5-carboxamide,N-hydroxy-4-methyl-(9CI).
Check Digit Verification of cas no
The CAS Registry Mumber 77196-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,9 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77196-89:
(7*7)+(6*7)+(5*1)+(4*9)+(3*6)+(2*8)+(1*9)=175
175 % 10 = 5
So 77196-89-5 is a valid CAS Registry Number.
77196-89-5Relevant academic research and scientific papers
Process for making 5-mercapto-1,2,3-triazoles
-
, (2008/06/13)
A process for making 5-mercapto-1,2,3-triazoles of the formula STR1 wherein R1 is hydrogen or a C1 -C4 -alkyl which may also be substituted, the said process comprising (1) as a first step reacting a solution of 1,2,3-thiadiazole-5-carbohydroxamic acid derivative of the formula STR2 wherein R1 has the meaning as above and R2 is hydrogen or a univalent metal equivalent in an inert organic solvent in the presence of an acid acceptor with a solution in an inert organic solvent of an acid halide of the formula so as to form an acylated 1,2,3-thiadiazole-5-carbohydroxamic acid derivative (2) reacting as a solution in an inert organic solvent the carbohydroxamic acid derivative just obtained with an alcohol or phenol of the formula so as to form a (1,2,3-thiadiazole-5-yl)-carbamic acid ester (3) then treating the thus obtained carbamic acid ester with an acetic or basic catalyst to form the 5-amino-1,2,3-thiadiazole (4) whereupon the said amino thiadiazole is subject to a rearrangement in the presence of a base followed by isolation of the product of the reaction.
