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N-cyclohexyl-2,2-difluoroacetamide is a chemical compound with the molecular formula C8H12F2NO. It is a derivative of acetamide, featuring a cyclohexyl group attached to the nitrogen atom and two fluorine atoms on the carbonyl carbon. N-cyclohexyl-2,2-difluoroacetamide is known for its potential applications in pharmaceuticals and agrochemicals, particularly as a building block for the synthesis of various active ingredients. Its unique structure, with the fluorine atoms enhancing metabolic stability and lipophilicity, makes it an interesting candidate for drug development. The compound is typically synthesized through various chemical reactions and is subject to strict safety and handling protocols due to its potential reactivity and toxicity.

772-52-1

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772-52-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 772-52-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,7 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 772-52:
(5*7)+(4*7)+(3*2)+(2*5)+(1*2)=81
81 % 10 = 1
So 772-52-1 is a valid CAS Registry Number.

772-52-1Downstream Products

772-52-1Relevant academic research and scientific papers

Highly chemoselective difluoromethylative homologation of iso(thio)cyanates: Expeditious access to unprecedented α,α-difluoro(thio)amides

Miele, Margherita,D'Orsi, Rosarita,Sridharan, Vellaisamy,Holzer, Wolfgang,Pace, Vittorio

, p. 12960 - 12963 (2019)

The new motif-α,α-difluoromethyl thioamide-has been assembled starting from isothiocyanate (as thioamide precursor) and a formal difluoromethyl-carbanion generated from commercially available TMSCHF2. Upon proper activation of this reagent with

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