77201-79-7Relevant academic research and scientific papers
Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones
Castagnolo, Daniele,Manetti, Fabrizio,Radi, Marco,Bechi, Beatrice,Pagano, Mafalda,De Logu, Alessandro,Meleddu, Rita,Saddi, Manuela,Botta, Maurizio
experimental part, p. 5716 - 5721 (2009/12/09)
Two series of novel rigid pyrazolone derivatives were synthesized and evaluated as inhibitors of Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis. Two of these compounds showed a high activity against MTB (MIC = 4 μg/mL). The newly sy
