77205-78-8 Usage
Physical State
Yellow powder
Solubility
Soluble in water, dimethyl sulfoxide (DMSO), and N-methyl-2-pyrrolidone (NMP)
Molecular Weight
379.9 g/mol
Melting Point
230-240°C (dec)
Properties
Tetrazolium salt, redox indicator
Function
Measures the metabolic activity of cells by being reduced by living cells to form an insoluble formazan product, allowing for the quantification of viable cells
Applications
Research and clinical settings to assess the effects of drugs, toxins, and other compounds on cell viability and proliferation; testing the efficacy of antimicrobial agents; screening for anticancer drugs
Advantages
Reliable and sensitive indicator of cellular metabolic activity
Usage
Widely used in the field of cell biology and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 77205-78-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,0 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77205-78:
(7*7)+(6*7)+(5*2)+(4*0)+(3*5)+(2*7)+(1*8)=138
138 % 10 = 8
So 77205-78-8 is a valid CAS Registry Number.
77205-78-8Relevant academic research and scientific papers
Method of measuring substance in sample using a redox reaction
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, (2008/06/13)
A highly reliable method of measuring an analyte in a sample using a redox reaction. In this method, a tetrazolium compound is added to a sample prior to the redox reaction so as to eliminate the influence of any reducing substance in the sample, then a reducing substance or an oxidizing substance derived from the analyte is formed, the quantity of the formed substance derived from the analyte is measured by the redox reaction, and the quantity of the analyte is determined from the quantity of the formed substance derived from the analyte. As the tetrazolium compound, for example, 2-(4-iodophenyl)-3-(2,4-dinitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium salt can be used.
