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1,4-Methano-1H-oxazolo[3,4-a]quinolinone is a heterocyclic organic compound characterized by a unique structure that fuses an oxazole ring with a quinoline ring through a methylene bridge. 1,4-methano-1H-oxazolo<3,4-a>quinolinone is of interest in medicinal chemistry due to its potential applications as a scaffold for the development of new drugs. The oxazole ring contributes to the molecule's stability and reactivity, while the quinoline moiety is known for its diverse biological activities. Research into this class of compounds often focuses on their ability to interact with various biological targets, such as enzymes and receptors, which could lead to the discovery of new therapeutic agents. The synthesis and modification of 1,4-methano-1H-oxazolo[3,4-a]quinolinone derivatives are active areas of study, aiming to optimize their pharmacological properties for specific medical applications.

77220-00-9

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77220-00-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77220-00-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,2 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77220-00:
(7*7)+(6*7)+(5*2)+(4*2)+(3*0)+(2*0)+(1*0)=109
109 % 10 = 9
So 77220-00-9 is a valid CAS Registry Number.

77220-00-9Downstream Products

77220-00-9Relevant academic research and scientific papers

Regiochemistry of Intramolecular Munchnone Cycloadditions: Preparative and Mechanistic Implications

Padwa, Albert,Gingrich, Henry L.,Lim, Richard

, p. 2447 - 2456 (2007/10/02)

A series of munchnone derivatives containing an internal ? bond were generated in situ by treating several N-(o-allylphenyl)alanines with acetic anhydride.The major product obtained corresponded to intramolecular 1,3-dipolar cycloaddition of the mesoionic

Regiochemical aspects associated with the intramolecular 1,3-dipolar cycloaddition reactions of munchnone derivatives

Padwa, Albert,Gingrich, Henry L.,Lim, Richard

, p. 3419 - 3422 (2007/10/02)

The regioselectivity of the internal cycloaddition of a series of N-(o-allylphenyl) substituted munchnones has been found to be markedly dependent on the substituent groups present.

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