77227-90-8

Usage

Uses

Used in Industrial and Agricultural Applications:
2-methyl-4-(trifluoromethyl)phenol is utilized as a bacteriostat and fungicide, serving to inhibit the growth of bacteria and fungi in various settings. Its effectiveness in controlling microbial growth makes it a valuable asset in preserving the quality and safety of products in these industries.
Used in Pharmaceutical Production:
As an intermediate in the synthesis of pharmaceuticals, 2-methyl-4-(trifluoromethyl)phenol plays a crucial role in the development of new drugs. Its chemical properties allow it to be a building block for creating a range of medicinal compounds, contributing to advancements in healthcare.
Used in Organic Compound Synthesis:
2-methyl-4-(trifluoromethyl)phenol is also employed as an intermediate in the production of other organic compounds, highlighting its importance in the realm of organic chemistry and the creation of novel materials and substances with potential applications in various fields.
Used in Environmental Research:
2-methyl-4-(trifluoromethyl)phenol has been identified as a potential environmental contaminant, prompting research into its impact on human health and the environment. This role is significant for understanding and mitigating the effects of chemical contaminants in ecosystems and on public health.

Upstream product

• 1689509-92-9 4,4,5,5-tetramethyl-2-(2-methyl-4-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane 
• 929000-62-4 1-bromo-2-methyl-4-(trifluoromethyl)benzene 

Downstream Products

• 502623-84-9 dimethyl 2-methyl-4-(trifluoromethyl)phenyl phosphate 

Relevant academic research and scientific papers

MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS

Methods are provided for modulating MRGPR X4 generally, or for treating a MRGPR X4 dependent condition more specifically, by contacting the MRGPR X4 or administering to a subject in need thereof, respectively, an effective amount of a compound having the structure of Formula (I): (I) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein n, x, A, Q1, Q2, Z, R, R1, R2, R3, R4 and R5 are as defined herein. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.

UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF

Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.

ANTICANCER COMPOUNDS

The invention provides compounds having the general formula I: and salts thereof, wherein the variables RA, RB, RC, L1, L2, L3, A, B, C, X, Y, Z, E, m, n, and p have the meaning as describe

N-(1-Benzyl-3,5-dimethyl?1H?pyrazol-4-yl)benzamides: Antiproliferative activity and effects on mTORC1 and autophagy

Guided by antiproliferative activity in MIA PaCa-2 cells, we have performed preliminary structure?activity relationship studies on N-(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)benzamides. Two selected compounds showed submicromolar antiproliferative activity

Syntheses and bioactivity of o- or p-trifluoromethylphenyl phosphates

o- and p-Trifluoromethylphenyl phosphates designed as mechanism-based phosphotyrosine phosphatase inactivators have been prepared. Some of them show herbicidal activities.