7724-28-9

Basic information

• Product Name: HYDROXY-1,4-BUTANEDIAL
• Synonyms: HYDROXY-1,4-BUTANEDIAL
• CAS NO: 7724-28-9
• Molecular Formula: C₄H₆O₃
• Molecular Weight: 102.09
• Mol File: 7724-28-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 232.9±35.0 °C(Predicted)
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• PKA: 12.60±0.20(Predicted)
• CAS DataBase Reference: HYDROXY-1,4-BUTANEDIAL(CAS DataBase Reference)
• NIST Chemistry Reference: HYDROXY-1,4-BUTANEDIAL(7724-28-9)
• EPA Substance Registry System: HYDROXY-1,4-BUTANEDIAL(7724-28-9)

Safety Data

• Hazardous Substances Data: 7724-28-9(Hazardous Substances Data)

Upstream product

• 3675-13-6 cis-butenedial 
• 332-77-4 2,5-dihydro-2,5-dimethoxyfuran 
• 131543-46-9 Glyoxal 
• 75-07-0 acetaldehyde 
• 874005-61-5 2,5-diethoxy-tetrahydro-furan-3-ol 

Downstream Products

• 42890-76-6 (S)-1,2,4-butanetriol 

Relevant articles and documents

Synthesis of the 2β,3β-, 2α,3β-, 2β,3α- and 2α,3α-isomers of 6β-hydroxy-3-(p-tolyl)tropane-2-carboxylic acid methyl ester

6-Hydroxytropanone (8) was synthesized by a Mannich type condensation between acetonedicarboxylic acid, methylamine hydrochloride, and the hydrolysis product of 2,5-dimethoxydihydrofuran and was used as the key intermediate for the synthesis of the four r

Total Synthesis of (±)-Scopolamine: Challenges of the Tropane Ring

Scopolamine was synthesized using 6,7-dehydrotropine as a key intermediate. Rhodium-catalyzed [4 + 3] cycloaddition chemistry and a modified Robinson-Sch?pf reaction were each independently evaluated for their utility in constructing the tropane core. Both synthetic approaches gave comparable overall yields.

Syntheses of (-)-pelletierine and (-)-homopipecolic acid

Enantiomeric syntheses of (-)-homopipecolic acid and (-)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer-Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines. The Royal Society of Chemistry 2012.