77244-88-3Relevant academic research and scientific papers
8-Quinolinesulfone(3-nitro-1,2,4-triazolide), a New Effective Condensing Agent in the Oligonucleotide Synthesis
Engels, Joachim,Krahmer, Ute,Zsolnai, Laszlo,Huttner, Gottfried
, p. 745 - 753 (2007/10/02)
The synthesis of the dinucleoside diphosphate 10 with 2',5'-linkage according to the phosphotriester method is described.Starting from the triester 7 we compared the condensation of 8 and 9 with several sulfonazolides. 8-Quinolinesulfone(3-nitro-1,2,4-tri
4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL HYDROGEN PHOSPHATE: A USEFUL PHOSPHORYLATING AGENT FOR GUANOSINE 3'-PHOSPHOTRIESTER
Takaku, Hiroshi,Kamaike, Kazuo,Kasuga, Kenichi
, p. 197 - 200 (2007/10/02)
5'-O-Dimethoxytrityl-2'-O-tetrahydropyranyl-N2-benzoylguanosine smoothly reacts with 4-chlorophenyl 5-chloro-8-quinolyl hydrogen phosphate in the presence of 8-quinolinesulfonyltetrazolide (QS-te) to give 5'-O-dimethoxytrityl-2'-O-tetrahydropyr
