77266-69-4

Basic information

• Product Name: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester
• Synonyms: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester;Ethyl 4-(2-aMinoethyl)benzoate;RBLUWLZGAZETKS-UHFFFAOYSA-N
• CAS NO: 77266-69-4
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• Mol File: 77266-69-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(77266-69-4)
• EPA Substance Registry System: Benzoic acid, 4-(2-aMinoethyl)-, ethyl ester(77266-69-4)

Safety Data

• Hazardous Substances Data: 77266-69-4(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1199-69-5 4-(2-aminoethyl)benzoic acid 
• 52062-92-7 4-(2-bromoethyl)benzoic acid 
• 74003-31-9 4-bromoethylbenzoic acid ethyl ester 
• 83901-88-6 4-cyanomethylbenzoic acid ethyl ester 
• 26496-94-6 Ethyl 4-(bromomethyl)benzoate 
• 60531-36-4 4-(2-amino-ethyl)-benzoic acid hydrochloride 
• 524743-24-6 ethyl 4-(2-phthalimidoethyl)benzoate 
• 72054-56-9 4-(2-bromoethyl)benzonitrile 

Downstream Products

• 65779-35-3 ethyl 4-[2-(fluorene-9-carboxamido)-ethyl]-benzoate 
• 69732-19-0 4-[2-(2-9H-Fluoren-9-yl-propionylamino)-ethyl]-benzoic acid ethyl ester 
• 113747-43-6 N-[2-(4-carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-acetylamino-4-methyl-thiazol-5-yl)ethanamine 
• 65779-40-0 4-[2-(2-10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl-acetylamino)-ethyl]-benzoic acid 
• 65779-36-4 4-{2-[(9H-Fluorene-9-carbonyl)-amino]-ethyl}-benzoic acid 
• 65779-44-4 4-[2-(2-9,10-Dihydro-anthracen-9-yl-acetylamino)-ethyl]-benzoic acid 
• 69732-20-3 4-[2-(2-9H-Fluoren-9-yl-propionylamino)-ethyl]-benzoic acid 
• 65779-42-2 4-{2-[2-(2,6-Dimethyl-9H-fluoren-9-yl)-acetylamino]-ethyl}-benzoic acid 
• 113753-36-9 N-[2-(4-Carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-benzoylamino-4-methyl-thiazol-5-yl)ethanamine 

Relevant articles and documents

Overcoming inaccessibility of fluorinated imines-synthesis of functionalized amines from readily available fluoroacetamides

Although imines are convenient substrates for the synthesis of functionalized amines, they may be hard to obtain, as in the case of fluorinated imines. To aid in overcoming this issue, we propose a protocol of corresponding amine synthesis from simple fluoroacetic acid-derived amides using Schwartz's reagent.

MTH1 INHIBITORS FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS

A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment of autoimmune diseases and inflammatory conditions.

5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, an optionally substituted lower alkenyl group, a cycloalkyl group or a lower acyl group etc.; Q is a hydrogen atom or an optionally substituted lower alkyl group; and Z is a hydrogen atom or a hydroxy group etc., or a pharmaceutically acceptable salt thereof, which exert a potent and selective activated blood coagulation factor X inhibitory activity and is useful as an agent for the prevention or treatment of a disease occurred associating an activated blood coagulation factor X, a pharmaceutical composition comprising the same and an intermediate thereof. These compounds are useful as preventives or remedies for various diseases such as brain infarction, cerebral thrombosis, cerebral embolism, TIA, cerebral vascular jerk, Alzheimer's diseases, myocardial infarction, heart attack, heart failure, thrombosis, pulmonary infarction and pulmonary embolism.