77270-15-6

Basic information

• Product Name: 1-hexyl-2,5-diphenyl-1H-pyrrole
• Synonyms: 1-hexyl-2,5-diphenyl-1H-pyrrole
• CAS NO: 77270-15-6
• Molecular Weight: 303.447
• Mol File: 77270-15-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-hexyl-2,5-diphenyl-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-hexyl-2,5-diphenyl-1H-pyrrole(77270-15-6)
• EPA Substance Registry System: 1-hexyl-2,5-diphenyl-1H-pyrrole(77270-15-6)

Safety Data

• Hazardous Substances Data: 77270-15-6(Hazardous Substances Data)

Upstream product

• 2085-90-7 1,4-diphenyl-1,4-butanediol 
• 111-27-3 hexan-1-ol 
• 111-26-2 hexan-1-amine 
• 536-74-3 phenylacetylene 
• 495-71-6 phenacylacetophenone 

Relevant articles and documents

Organic synthesis in deep eutectic solvents: Paal-Knorr reactions

Deep eutectic solvents (the combination of either urea or glycerol with choline chloride) are effective solvents/catalysts for Paal-Knorr reactions to form pyrroles of furans. The reaction conditions are quite mild and do not require the addition of an additional Bronsted or Lewis acid catalyst. Given the inexpensive, non-toxic, and recyclable nature of the DES, these reaction conditions are simple and highly environmentally friendly.

Acceptorless Dehydrogenative Coupling Using Ammonia: Direct Synthesis of N-Heteroaromatics from Diols Catalyzed by Ruthenium

The synthesis of N-heteroaromatic compounds via an acceptorless dehydrogenative coupling process involving direct use of ammonia as the nitrogen source was explored. We report the synthesis of pyrazine derivatives from 1,2-diols and the synthesis of N-substituted pyrroles by a multicomponent dehydrogenative coupling of 1,4-diols and primary alcohols with ammonia. The acridine-based Ru-pincer complex 1 is an effective catalyst for these transformations, in which the acridine backbone is converted to an anionic dearomatized PNP-pincer ligand framework.