77270-59-8

Upstream product

• 77270-58-7 3-(2-Methoxy-ethoxymethoxy)-2-nitro-phenol 

Downstream Products

• 77270-69-0 (5aR,9aS)-4-Acetyl-8-methoxy-2,7-dimethyl-5,10-dioxo-9-phenylsulfanyl-3,4,5,5a,6,9,9a,10-octahydro-2H-naphtho[2,3-b][1,4]oxazine-2-carboxylic acid methyl ester 
• 77270-63-4 4-Benzyl-5-(2-methoxy-ethoxymethoxy)-2-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-2-carboxylic acid methyl ester 
• 77270-62-3 4-Benzyl-5-(2-methoxy-ethoxymethoxy)-3,4-dihydro-2H-benzo[1,4]oxazine-2-carboxylic acid 
• 77270-61-2 4-Benzyl-5-(2-methoxy-ethoxymethoxy)-3,4-dihydro-2H-benzo[1,4]oxazine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Studies Directed toward the Total Synthesis of the Rubradirin Antibiotics. 2. Synthesis of the Unique Morpholinonaphthoquinone Chromophore: A Lesson in Diels-Alder Regiocontrol by Diene Substituent Selection

A Diels-Alder approach to the aromatic/heterocyclic portion of the rubradirins is detailed.