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1-Piperazinecarboxylic acid, 4-[(4-hydroxyphenyl)methyl]-, 1,1-dimethylethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

77278-44-5

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77278-44-5 Usage

Molecular weight

405.53 g/mol

Chemical structure

1-Piperazinecarboxylic acid, 4-[(4-hydroxyphenyl)methyl]-, 1,1-dimethylethyl ester

Purpose

Flibanserin is commonly used in the treatment of hypoactive sexual desire disorder in women.

Mechanism of action

Flibanserin works by affecting serotonin receptor activity in the brain and has been shown to increase sexual desire and reduce distress in women who suffer from low libido.

Receptor selectivity

Flibanserin is a selective serotonin receptor agonist.

Development history

Flibanserin was originally developed as an antidepressant but is now primarily used as a medication for sexual dysfunction.

Regulatory approval

Flibanserin has been approved by the FDA for use in premenopausal women.

Ongoing research

The use of Flibanserin is still being studied for other potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 77278-44-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,7 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 77278-44:
(7*7)+(6*7)+(5*2)+(4*7)+(3*8)+(2*4)+(1*4)=165
165 % 10 = 5
So 77278-44-5 is a valid CAS Registry Number.

77278-44-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4-hydroxybenzyl)piperazin-1-carboxylic acid tert-butyl ester

1.2 Other means of identification

Product number -
Other names tert-butyl 4-(4-hydroxybenzyl)piperazine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77278-44-5 SDS

77278-44-5Downstream Products

77278-44-5Relevant academic research and scientific papers

Assay for benzylpiperazine and metabolites

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, (2017/03/28)

The invention relates to the detection and quantification of 1-benzylpiperazine and its metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications.

PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS

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Page/Page column 68, (2015/06/25)

New pyrazolopyridmiin-2-yl derivatives are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

NOVEL AMINOMETHYL-PHENOL DERIVATIVES AS ANTIMALARIAL AGENTS

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Page/Page column 60-61, (2014/05/24)

The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention

Compounds and methods for treatment of amyloid-B-peptide related disorders

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Page/Page column 16, (2008/06/13)

The present invention relates to compounds, preparation and uses thereof, particularly in the pharmaceutical industry. The present invention discloses novel compounds of the following formula (I) more particularly useful for the treatment of Alzheimer's d

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