77279-89-1Relevant academic research and scientific papers
Design, synthesis, and insecticidal activities of novel monohalovinylated pyrethroids
Zheng, Zubiao,Wang, Jing,Zhang, Deyan,Guan, Xixia,Gao, Shuxu,Chen, Zizhan,Zou, Xinzhuo
experimental part, p. 1171 - 1177 (2011/10/30)
A series of novel monohalovinylated pyrethroids are designed and synthesized to replace one halo atom with a hydrogen atom on the double bond of dihalopyrethroids. Bioassays indicate that some of the synthesized compounds, such as 3j and 1j, exhibit high insecticidal activities against mosquitoes (Culex pipiens pallens), oriental armyworms (Mythimna separata), alfalfa aphids (Aphis medicagini), and carmine spider mites (Tetranychus cinnabarinus). Photolytic results of E-cis-1j suggest that monohalovinylated pyrethroids are photodegraded more easily than compound 12.
Structure-based design, synthesis, and study of potent inhibitors of β-ketoacyl-acyl carrier protein synthase III as potential antimicrobial agents
Nie, Zhe,Perretta, Carin,Lu, Jia,Su, Ying,Margosiak, Stephen,Gajiwala, Ketan S.,Cortez, Joseph,Nikulin, Victor,Yager, Kraig M.,Appelt, Krzysztof,Chu, Shaosong
, p. 1596 - 1609 (2007/10/03)
Fatty acid biosynthesis is essential for bacterial survival. Components of this biosynthetic pathway have been identified as attractive targets for the development of new antibacterial agents. FabH, β-ketoacyl-ACP synthase III, is a particularly attractiv
Synthesis and insecticidal activity of some 1,3,4-oxadiazole derivatives containing phenoxyfluorophenyl group
Mohan,Vishalakshi,Bhat,Rao,Kendappa
, p. 1798 - 1801 (2007/10/03)
The synthesis of a few 1,3,4-oxadiazoles 5a-e is described. 4-Fluoro-3-phenoxybenzoic acid 2 is prepared starting from 4-Fluoro-3- phenoxybenzaldehyde 1. Esterification of 2 with methanol in the presence of H2SO4 gives the correspond
Synthesis of some new fluorine containing 1,3,4-oxadiazole derivatives as potential antibacterial and anticancer agents
Bhat, K. Subrahmanya,Karthikeyan,Holla, B. Shivarama,Shetty, N. Suchetha
, p. 1765 - 1769 (2007/10/03)
The synthesis of a number of 1,3,4-oxadiazole derivatives have been described. 2,4-Dichloro-5-fluorobenzoyl hydrazine 1 on reacting with aromatic acids in presence of phosphorus oxychloride affords 2,5-disubstituted-1,3,4- oxadiazoles 2a-j. Aroyl hydrazine on reacting with carbon disulphide under basic condition gives oxadiazol-2-thione 3. Oxadiazol-2-thiones are regioselectively aminomethylated to give N-aminomethylated products 4a-c. Further, 3 undergoes regioselective alkylation on treating with alkyl/aroyl halides to give S-alkyl/aroyl products 5a-c. All the newly synthesized compounds have been screened for their antibacterial activity. Most of them show promising antibacterial activity. Also two out of nine compounds show anticancer activity in the primary anticancer assay.
Synthesis of some new fluorine containing thiadiazolotriazinones as potential antibacterial agents
Holla, B. Shivarama,Bhat, K. Subrahmanya,Shetty, N. Suchetha
, p. 2193 - 2199 (2007/10/03)
2,4-dichloro-5-fluorophenyl, 4-fluoro-3-(Phenoxy)phenyl, 4-fluorophenyl groups are known pharmacophores and can be used in the synthesis of new biologically active molecules. Therefore, 4-amino-6-arylmethyl-3-mercapto-1,2,4- triazin5(4H)-ones 1 are conden
Halogenated diphenyl ether derivatives
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, (2008/06/13)
Compounds of the Formula: STR1 wherein X is selected from bromine and chlorine useful as intermediates in the preparation of insecticidal compounds.
