77291-90-8

Basic information

• Product Name: (3R,5R)-(-)-3,5-HEPTANEDIOL
• Synonyms: (3R,5R)-(-)-3,5-HEPTANEDIOL;(3R,5R)-3,5-HEPTANEDIOL;(3R,5R)-(-)-3,5-Heptanediol,99%
• CAS NO: 77291-90-8
• Molecular Formula: C7H16O2
• Molecular Weight: 132.2
• Product Categories: Chiral Compounds;Diols;organic alcohol
• Mol File: 77291-90-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 52-53℃
• Boiling Point: 110℃ (12 Torr)
• Appearance: colorless/solid
• Density: 0.945±0.06 g/cm3(Predicted)
• PKA: 14.71±0.20(Predicted)
• CAS DataBase Reference: (3R,5R)-(-)-3,5-HEPTANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R)-(-)-3,5-HEPTANEDIOL(77291-90-8)
• EPA Substance Registry System: (3R,5R)-(-)-3,5-HEPTANEDIOL(77291-90-8)

Safety Data

• Hazardous Substances Data: 77291-90-8(Hazardous Substances Data)

Usage

General Description

(3R,5R)-(-)-3,5-HEPTANEDIOL is a chiral compound with the molecular formula C7H16O2. It is a colorless, viscous liquid that is used as a solvent and a chemical intermediate in the synthesis of pharmaceuticals and other organic compounds. The compound exists in two enantiomeric forms, (3R,5R)-(-)-3,5-HEPTANEDIOL and (3S,5S)-(+)-3,5-HEPTANEDIOL, with the former being the naturally occurring form. It is commonly used in the production of perfumes, resins, and plasticizers, and has potential applications in various fields including the pharmaceutical and fragrance industries. Additionally, (3R,5R)-(-)-3,5-HEPTANEDIOL is also used in the manufacturing of flavors and fragrances due to its pleasant odor.

Upstream product

• 7424-54-6 3,5-heptanedione 

Relevant articles and documents

Enantioselective preparation of 2,4-disubstituted azetidines

Chiral C2-symmetric N-benzylazetidines have been conveniently prepared from optically pure anti-1,3-diols without loss of enantiomeric purity. N- Debenzylation led to the corresponding N-unsubstituted azetidines, which were then subjected to palladium-catalysed coupling reactions with aryl bromides to afford chiral N-arylazetidines. (R,R)-N-Benzyl-2,4-dimethylazetidine has been employed in the synthesis of a new cyclopalladated complex, which can be used, for instance, as a chiral recognition agent for phosphorus ligands.

Enantioselective synthesis ofanti 1, 3-diols via ru(ii)-catalyzed hydrogénations

The homogeneous ruthenium-catalyzed hydrogénation of new symmetrical 1, 3-diketones has been achieved with various ligands including SKEWPHOS and Me-DuPHOS. Complete conversions with enantiomeric and diastereomeric excesses up to 99% were obtained. This represents a new catalytic application of the chiral ligands above. Thieme Stuttgart.