77294-34-9

Upstream product

• 59513-85-8 1-benzyl-5-methoxy-2-methyl-indole-3-carboxylic acid ethyl ester 

Downstream Products

• 77294-47-4 1-Benzyl-5-methoxy-2-methyl-1H-indole-3-carboxylic acid N'-hydroxymethyl-hydrazide 
• 77811-27-9 1-benzyl-5-methoxy-2-methyl-3-(1',3',4'-oxadiazol-2'-yl)indole 
• 77294-49-6 1-Benzyl-5-hydroxymethyl-7-methoxy-2-methyl-1,4,5,6-tetrahydro-[1,2]diazepino[4,5,6-cd]indol-3-one 
• 77294-40-7 1-Benzyl-5-methoxy-2-methyl-1H-indole-3-carboxylic acid N'-acetyl-hydrazide 

Relevant academic research and scientific papers

Synthesis of Substituted Diazepinoindol-4-ones

Various substituted ethyl 5-hydroxy-2-methylindole-3-carboxylates have been prepared by Nenitzescu reaction.These on condensation with hydrazine hydrate give the respective carboxyhydrazides, which react with formamide, acetic anhydride-acetic acid and be

Synthesis of Substituted Oxadiazolylindoles

Indole-3-carboxyhydrazides (2a-d) are prepared and reacted with triethyl orthoformate to yield 3-(1',3',4'-oxadiazol-2'-yl)indoles (4a1-d1). 2a-d on reaction with benzaldehyde yield the corresponding schiff bases (3a-c).These on oxidative cyclodehydrogenation give 3-(5'-phenyl-1',3',4'-oxadiazol-2'-yl)indoles (4a2-d2). 2a-d also react with CS2 to produce 3-(5'-thione-1',3',4'-oxadiazol-2'-yl)indoles (5a-c) which undergo Mannich reaction with formaldehyde and 2-aminothiazoles to yield 7a-d.