77299-79-7Relevant articles and documents
Aerobic oxidative α-iodination of carbonyl compounds using molecular iodine activated by a nitrate-based catalytic system
Prebil, Rok,Stavber, Stojan
supporting information, p. 5643 - 5647 (2014/12/11)
The novel reaction system comprising air/NH4NO3(cat.)/I2/H2SO4(cat.)is introduced as a simple, safe, cheap, efficient, and regioselective mediator for direct aerobic oxidative α-iodination of aryl, heteroaryl, alkyl, and cycloalkyl methyl ketones. The reaction system enabled the moderate to quantitative regioselective iodination of a large range of different methyl ketone derivatives including those bearing oxidizable heteroatom (S, N) substituents. Several activated aromatic compounds were also efficiently and selectively iodinated. The practical applicability of the presented reaction system was shown on 20 mmol scale under ambient pressure and 100% conversion of substrate was achieved.
Iodination of enol acetates and 1,3-diones using N-iodosaccharin
Dolenc, Darko
, p. 2917 - 2924 (2007/10/03)
Iodination of enol acetates and 1,3-diones with N-iodosaccharin yielding the corresponding α-iodoketones and 2-iodo-1,3-diones is presented. Reactions are carried out at room temperature under neutral conditions and in short reaction times.
Syntheses of α-Iodocarbonyl Compounds Using Bis(sym-collidine)Iodine(I) Tetrafluoroborate/Dimethyl Sulfoxide
Evans, Robert D.,Schauble, J. Herman
, p. 727 - 730 (2007/10/02)
I(1+)(Collidine)2BF4(1-)/DMSO has been found to be a convenient reagent for the direct conversion of alkenes to α-iodocarbonyl compounds.Using conformationally biased alkenes, the reactions proceed stetreospecifically giving axial iodoketones.Application of the reagent in reactions with unsaturated carbohydrates provides a unique method for the conversion of certain glycals to their corresponding α-iodo-α,β-unsaturated lactones.