77308-57-7Relevant academic research and scientific papers
Sensitizing compound, photosensitive resin composition, and applications thereof
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Paragraph 0066-0068, (2021/01/30)
The invention provides a sensitizing compound, a photosensitive resin composition and applications of the sensitizing compound and the photosensitive resin composition. The sensitizing compound has astructure as shown in a general formula (I), wherein R1a, R2a, R3a, R4a, R1b, R2b, R1c, R2c, R3c and R4c each independently represent hydrogen, linear or branched alkyl, cycloalkyl, cycloalkyl alkyl,alkyl cycloalkyl, -NO2, -ORA, -CORA, -COORA, -SRA, -SO2RA or -CONRARB; in the general formula (I), A represents a group shown as the specification, *O*, *S*, a group shown as the specification or a group shown as the specification; or A in the general formula (I) represents -CR1R2. Compared with the common sensitizer at present, the compound with the general formula (I) has a large molecular weight and stable structure, so that the compound has the characteristics of high sensitization, difficulty in sublimation, low migration, easy preparation and low cost.
The rotameric (R*,S*)- and (R*,R*)-biaryl-3,3′-diphthalides of polyphenylene series
Yangirov, Tagir A.,Fatykhov, Akhnef A.,Sedova, Elvira A.,Khalilov, Leonard M.,Meshcheryakova, Ekaterina S.,Ivanov, Sergey P.,Salazkin, Sergey N.,Kraikin, Vladimir A.
, p. 1282 - 1292 (2019/02/03)
A wide range of diastereomeric pairs of biaryl-3,3′-diphthalides with aromatic (heteroaromatic) substituents of polyphenylene series (including halogen substituted) was synthesized. All of them were separated and characterized by the methods of X-ray analysis, HPLC, IR-, 1H and 13C NMR spectroscopy. It was determined that solubility, tendency to adsorption and related to it retention times, chemical shifts of equivalent hydrogen and carbon atoms of biaryl-3,3′-diphthalides diastereoisomers are determined firstly by the stereo-electronic effects of two adjacent strongly polar phthalide groups. It was shown that both in crystalline phase and in solution all the diphthalides, regardless of the chemical structure of their substituents, are existing as stable rotamers with cis or synperiplanar (chiral forms) and trans or antiperiplanar (meso-forms) conformation.
Synthesis and Biological Evaluation of New Phthalazinone Derivatives as Anti-Inflammatory and Anti-Proliferative Agents
Hameed, Alhamzah Dh.,Ovais, Syed,Yaseen, Raed,Rathore, Pooja,Samim, Mohammed,Singh, Surender,Sharma, Kalicharan,Akhtar, Mymona,Javed, Kalim
, p. 150 - 159 (2016/02/09)
The chemistry of phthalazine derivatives has been of increasing interest since many of these compounds have found many chemotherapeutic applications. So this study aims to synthesize a library of phthalazine derivatives and to investigate their anti-inflammatory and anti-proliferative activities. Sixteen new phthalazinone derivatives (2a-p) were synthesized and tested for their in vitro antiproliferative and in vivo anti-inflammatory activities. All the synthesized compounds were identified and characterized by IR, 1H NMR, 13C NMR spectroscopy, and MS. Two compounds, 2b and 2i, showed significant anti-inflammatory activity comparable with that of the standard drug etoricoxib in the carrageenan-induced rat paw edema model at 3 and 5 h, respectively. Three compounds (2h, 2j, and 2g) showed moderate sensitivity toward the renal cancer cell line UO-31. A library of new phthalazone compounds (2a-p) was synthesized as dual inhibitors (COX-2/LOX-5) and evaluated for their anti-inflammatory, anticancer activities. Two compounds showed significant anti-inflammatory activity comparable with that of the standard drug etoricoxib, whereas three compounds showed moderate sensitivity toward the renal cancer cell line UO-31.
Fonctionnalisation d'hydrocarbures aromatiques polycycliques. Introduction de fonctions alcool, acide ou amine sur le biphenyle, le fluorene ou le phenanthrene
Guilhemat, Robert,Pereyre, Michel,Petraud, Michel
, p. 334 - 344 (2007/10/02)
With aluminium chloride as a catalyst, 3-methyl-1,3-butanediol, a primary-tertiary diol, yielded Friedel-Crafts primary alcohols with fluorene and biphenyl.The monosubstituted derivatives have been characterized mainly by 13C nmr and polysubstituted products have been obtained with excess diol.With the same substrates and in the same conditions a tertiary-tertiary diol such as 2,5-dimethyl-2,5-hexanediol gave only mono or bicycloalkylated hydrocarbons.The reactions of phtalic anhydride with fluorene, biphenyl and phenanthrene have been studied and the monosubstituted products characterized mainly by 13C nmr by means of a relaxation reagent.Bifunctionalized derivatives were also obtained and identified in the case of fluorene and biphenyl.On the other hand, amino functional groups were introduced on fluorene either by transformation of acid functions or by more direct routes such as reaction with isatoic anhydride or p-toluenesulfonylanthranilic acid.Some results have been used for the functionalization of an industrial residue containing polycyclic aromatic hydrocarbons.
