77308-70-4

Basic information

• Product Name: (Z)-m-(trifluoromethyl)-α,β-dimethylcinnamic acid
• CAS NO: 77308-70-4
• Molecular Weight: 244.213
• Mol File: 77308-70-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-m-(trifluoromethyl)-α,β-dimethylcinnamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-m-(trifluoromethyl)-α,β-dimethylcinnamic acid(77308-70-4)
• EPA Substance Registry System: (Z)-m-(trifluoromethyl)-α,β-dimethylcinnamic acid(77308-70-4)

Safety Data

• Hazardous Substances Data: 77308-70-4(Hazardous Substances Data)

Upstream product

• 202664-53-7 2-fluoro-5-trifluoromethyl-acetophenone 
• 52094-29-8 (Z)-2-Methyl-3-(3-trifluoromethyl-phenyl)-but-2-enoic acid ethyl ester 

Downstream Products

• 77302-29-5 (Z)-2-Methyl-3-(3-trifluoromethyl-phenyl)-but-2-enoic acid cyclopropylamide 
• 77302-28-4 (Z)-2-Methyl-3-(3-trifluoromethyl-phenyl)-but-2-enoic acid amide 
• 344556-09-8 (Z)-2-Methyl-3-(3-trifluoromethyl-phenyl)-but-2-enoyl chloride 

Relevant articles and documents

Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them

Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them. Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, of the formula I in which the substituents have the meanings stated in the description, and their pharmaceutically suitable salts, are described. They are obtained by reacting a compound II with guanidine, in which R(1) to R(5) and R(A), R(B), R(C) and R(D) have the stated meaning, and L is a leaving group which easily undergoes nucleophilic substitution. Compounds I are excellent cardiovascular therapeutic agents.