773099-38-0Relevant academic research and scientific papers
INHIBITORS OF TRYPTOPHAN DIOXYGENASES (IDO1 AND TDO) AND THEIR USE IN THERAPY
-
Page/Page column 56; 57; 58; 59, (2016/02/29)
Pharmaceutical compositions comprising 3-aminoisoxazolopyridine compounds of the Formula I having IDO1 and/or TDO inhibitory activity are described, where W is CR1, N or N-oxide; X is CR2, N or N-oxide; Y is CR3, N or N-ox
Regioselective cross-coupling reactions of boronic acids with dihalo heterocycles
Houpis, Ioannis N.,Liu, Renmao,Wu, Yanfei,Yuan, Yukuan,Wang, Youchu,Nettekoven, Ulrike
experimental part, p. 6965 - 6968 (2010/11/17)
The carboxylic acid anion moiety has been used as a tunable directing group in the cross-coupling reaction of 2,6-dichloronicotinic acid and 2,5-dibromo-1,2,4-triazole derivatives producing selectively the 2- or 6-substituted nicotinic acids, while only the 5-substituted triazoles were obtained under a variety of conditions.
