773104-57-7

Upstream product

• 773104-58-8 (2E,5R,6S,7Z,9E,12R)-12-(tert-butyldimethylsilyloxy)-13-[(6R)-4-methoxymethoxy-5,6-dihydropyran-2-one-6-yl]-6-[(4-methoxyphenyl)methoxy]-5-methyl-2,7,9-tridecatrienal 
• 1025834-22-3 (R)-6-((R)-2-Hydroxy-pent-4-ynyl)-dihydro-pyran-2,4-dione 
• 773104-74-8 (6R)-6-[(2R)-2-hydroxypent-4-yn-1-yl]-4-methoxymethoxy-5,6-dihydropyran-2-one 
• 773104-83-9 (2E,5R,6S,7Z,9E,12R)-12-(tert-butyldimethylsilyloxy)-1-(tert-butyldiphenylsilyloxy)-13-[(6R)-4-methoxymethoxy-5,6-dihydropyran-2-one-6-yl]-6-[(4-methoxyphenyl)methoxy]-5-methyl-2,7,9-tridecatriene 
• 773104-65-7 (2E,5R,6S,7Z,9E,12R)-12-(tert-butyldimethylsilyloxy)-13-[(6R)-4-methoxymethoxy-5,6-dihydropyran-2-one-6-yl]-6-[(4-methoxyphenyl)methoxy]-5-methyl-2,7,9-tridecatrien-1-ol 
• 773104-60-2 (6R)-6-[(2R,4E)-2-tert-butyldimethylsilyloxy-5-iodopent-4-enyl]-4-methoxymethoxy-5,6-dihydropyran-2-one 
• 773104-61-3 (6R)-6-[(2R)-2-tert-butyldimethylsilyloxypent-4-yn-1-yl]-4-methoxymethoxy-5,6-dihydropyran-2-one 
• 640270-65-1 (3R)-3-{[tert-butyl(dimethyl)silyl]oxy}hex-5-ynenitrile 
• 640270-59-3 (3R)-3-{[tert-butyl(dimethyl)silyl]oxy}hex-5-ynal 
• 182681-88-5 (2R)-1-cyano-2-hydroxy-4-pentyne 
• 640270-66-2 (2RS,4R)-4-(tert-butyldimethylsilyloxy)-1-(2,2-dimethyl-1,3-dioxin-4-one-6-yl)-6-heptyn-2-ol 
• 640270-67-3 (4R)-4-(tert-butyldimethylsilyloxy)-1-(2,2-dimethyl-1,3-dioxin-4-one-6-yl)-6-heptyn-2-one 
• 640270-60-6 (4R)-1-(2,2-dimethyl-1,3-dioxin-4-one-6-yl)-4-hydroxy-6-heptyn-2-one 
• 640270-68-4 (2R,4R)-1-(2,2-dimethyl-1,3-dioxin-4-one-6-yl)-6-heptyne-2,4-diol 

Relevant academic research and scientific papers

Total synthesis of macquarimicins using an intramolecular Diels-Alder approach inspired by a biosynthetic pathway

A total synthesis of the macquarimicins A-C (1-3), novel natural products with intriguing tetra- or pentacyclic frameworks, has been achieved. The synthesis features an extensive investigation of the biosynthesis-based intramolecular Diels-Alder (IMDA) re