773104-76-0

Upstream product

• 377751-03-6 (3S,4R,6E)-1,1-dibromo-8-(tert-butyldiphenylsilyloxy)-3-[(4-methoxyphenyl)methoxy]-4-methyl-1,6-octadiene 
• 377751-08-1 (2S,3R,5E)-3-methyl-5-heptene-1,2,7-triol 
• 377751-07-0 (2E,5R,6S)-6,7-(isopropylidene)dioxy-5-methyl-2-hepten-1-ol 
• 377751-06-9 ethyl (2E,5R,6S)-6,7-(isopropylidene)dioxy-5-methyl-2-heptenoate 
• 377751-19-4 (E)-(R)-5-[(S)-2-(4-Methoxy-phenyl)-[1,3]dioxolan-4-yl]-hex-2-en-1-ol 
• 377751-09-2 (2E,5R,6S)-6-[(4-methoxyphenyl)methoxy]-5-methyl-2-heptene-1,7-diol 
• 377751-10-5 (2S,3R,5E)-7-(tert-butyldiphenylsilyloxy)-2-[(4-methoxyphenyl)methoxy]-3-methyl-5-hepten-1-ol 

Downstream Products

• 773104-81-7 (2E,5R,6S,7E,9Z)-1-(tert-butyldiphenylsilyloxy)-6-[(4-methoxyphenyl)methoxy]-5-methyl-12-(triphenylmethoxy)-2,7,9-dodecatriene 
• 773104-82-8 (2E,5R,6S,7E,9Z)-6-[(4-methoxyphenyl)methoxy]-5-methyl-12-(triphenylmethoxy)-2,7,9-dodecatrien-1-ol 
• 773104-63-5 (2E,5R,6S,7E,9Z)-6-[(4-methoxyphenyl)methoxy]-5-methyl-12-(triphenylmethoxy)-2,7,9-dodecatrienal 
• 377750-90-8 (1S,2S,3S,4Z,6S,7S,8R)-2-formyl-7-[(4-methoxyphenyl)methoxy]-8-methyl-3-[2-(triphenylmethoxy)ethyl]bicyclo[4.3.0]non-4-ene 
• 773104-77-1 (1E,3S,4R,6E)-8-(tert-butyldiphenylsilyloxy)-1-iodo-3-[(4-methoxyphenyl)methoxy]-4-methyl-1,6-octadiene 

Relevant academic research and scientific papers

Total synthesis of macquarimicins using an intramolecular Diels-Alder approach inspired by a biosynthetic pathway

A total synthesis of the macquarimicins A-C (1-3), novel natural products with intriguing tetra- or pentacyclic frameworks, has been achieved. The synthesis features an extensive investigation of the biosynthesis-based intramolecular Diels-Alder (IMDA) re