77317-54-5Relevant academic research and scientific papers
Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis
Akama, Tsutomu,Baker, Stephen J.,Zhang, Yong-Kang,Hernandez, Vincent,Zhou, Huchen,Sanders, Virginia,Freund, Yvonne,Kimura, Richard,Maples, Kirk R.,Plattner, Jacob J.
scheme or table, p. 2129 - 2132 (2009/12/07)
A series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. This compound is now in clinical development for the topical treatment of psoriasis and being pursued for the topical treatment of atopic dermatitis.
Method of antagonizing herbicides on soyabean and cotton
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, (2008/06/13)
Method of protecting legumes and cotton from herbicidal damage using a compound of formula: STR1 wherein R1 and R2 are hydrogen, halogen, alkoxy, alkyl, trihalomethyl, amino or hydroxy, Q is carboxy, x is 1, m is 1 or 2, and n is 1 or 2.
