7732-32-3

Basic information

• Product Name: 3,5-Dihydroxybenzhydrazide
• Synonyms: 3,5-DIHYDROXYBENZHYDRAZIDE;3,4-DIHYDROXYBENZHYDRAZIDE;LABOTEST-BB LT00455293;PROTOCATECHUIC HYDRAZIDE;3,5-DIHYDROXY-BENZOIC ACID HYDRAZIDE
• CAS NO: 7732-32-3
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
• Mol File: 7732-32-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 257 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.477g/cm³
• Refractive Index: 1.67
• PKA: 8.78±0.10(Predicted)
• BRN: 2642968
• CAS DataBase Reference: 3,5-Dihydroxybenzhydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dihydroxybenzhydrazide(7732-32-3)
• EPA Substance Registry System: 3,5-Dihydroxybenzhydrazide(7732-32-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 7732-32-3(Hazardous Substances Data)

Usage

General Description

3,5-Dihydroxybenzhydrazide is a chemical compound known for its antioxidant properties. It is commonly used as an additive in various skincare and cosmetic products due to its ability to protect against free radical damage and oxidative stress. Additionally, 3,5-Dihydroxybenzhydrazide has been shown to possess anti-inflammatory and anti-aging properties, making it a popular ingredient in anti-aging creams and serums. 3,5-Dihydroxybenzhydrazide is also being researched for its potential use in pharmaceuticals, particularly in the treatment of diseases related to oxidative stress and inflammation. Overall, 3,5-Dihydroxybenzhydrazide is a versatile chemical with numerous potential applications in both the cosmetic and pharmaceutical industries.

InChI:InChI=1/C7H8N2O3/c8-9-7(12)4-1-5(10)3-6(11)2-4/h1-3,10-11H,8H2,(H,9,12)

Upstream product

• 99-10-5 3,5-Dihydroxybenzoic acid 
• 4142-98-7 ethyl 3,5-dihydroxybenzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 

Downstream Products

• 1332355-94-8 (S)-N-(1-(2-(3,5-dihydroxybenzoyl)hydrazinyl)-4-methyl-1-oxopentan-2-yl)-3-nitrobenzenesulfonamide 
• 1119963-83-5 (E)-3,5-dihydroxy-N'-(2-hydroxybenzylidene)benzohydrazide 

Relevant articles and documents

Inhibitory potential of new phenolic hydrazide-hydrazones with a decoy substrate fragment towards laccase from a phytopathogenic fungus: SAR and molecular docking studies

Laccase from pathogenic fungi participates in both the delignification and neutralization of phytoantibiotics. Furthermore, it interferes with the hormone signaling in plants and catalyzes melanization. Infections of these pathogens contribute to loss in

Benzoyl hydrazone neuraminidase inhibitor and preparation method and application thereof

The invention provides a benzoyl hydrazone neuraminidase inhibitor. The inhibitor is characterized in that the structure of the inhibitor is shown in the formula I. The inhibitor has the advantage that according to the structural formula, the synthesized

Discovery of Novel Neuraminidase Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay

Neuraminidase (NA) is a significant therapeutic target for treating influenza. In this study, a new lead NA inhibitor AN-329/10738021 was discovered by structure-based virtual screening, molecular dynamics simulations, and bioassay validation. Optimization of lead AN-329/10738021, which holds a novel scaffold of N′-benzylidene benzohydrazone, leads to discovery of some novel NA inhibitors Y-1-Y-11. Compound Y-1 exerts the best inhibition activity (IC50 = 0.21 μM) against NA, which is better than oseltamivir carboxylate (OSC) (IC50 = 3.04 μM) and lead AN-329/10738021 (IC50 = 1.92 μM). Molecular docking analysis indicates that the good potency of Y-1 may be ascribed to the elongation of the benzylidene moiety of the molecule to the 430-cavity. The results of this study may offer useful reference for development of novel NA inhibitors.