7732-50-5

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(3S,3aR,6S)-6-iodohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one is used as a compound of interest in pharmaceutical research and drug development due to its unique stereochemistry, which may contribute to the activity and specificity of potential drugs.
Used in Medical Imaging:
(3S,3aR,6S)-6-iodohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one is used as a source of radioiodine in medical imaging, taking advantage of the iodine atom present in its structure to enhance imaging techniques.
Used in Organic Synthesis:
(3S,3aR,6S)-6-iodohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one is used as a precursor in organic synthesis, where its complex structure and the presence of iodine can be utilized to create new compounds with various applications.

Upstream product

• 934-30-5 5-norbornene-endo-2-carboxylic acid 

Downstream Products

• 91789-39-8 Trifluoro-acetic acid (1R,2S,4R,6S)-6-(toluene-4-sulfonyloxymethyl)-bicyclo[2.2.1]hept-2-yl ester 
• 91789-40-1 Trifluoro-acetic acid (1R,2S,4R,5R)-5-(toluene-4-sulfonyloxymethyl)-bicyclo[2.2.1]hept-2-yl ester 
• 91789-43-4 2-hydroxyheptyl 2-endo-(4-tolylsulphonyloxymethyl)norbornan-6-exo-yl ether 
• 91789-42-3 2-endo-(4-tolylsulphonyloxymethyl)norbornan-6-exo-yl formylmethyl ether 
• 91789-41-2 2-endo-(4-tolylsulphonyloxymethyl)norbornan-6-exo-ylprop-2-enyl ether 
• 86045-87-6 6-exo-hydroxynorbornan-2-endo-ylmethyl toluene-4-sulphonate 
• 91789-38-7 5-exo-hydroxynorbornan-2-endo-ylmethyl toluene-4-sulphonate 
• 50626-34-1 5-(Tosyloxymethyl)bicyclo<2.2.1>hept-2-ene 
• 120-74-1 endo-norbornenecarboxylic acid 

Relevant academic research and scientific papers

Multivalent alteration of quorum sensing in Staphylococcus aureus

Virulence in Staphylococcus aureus is strongly and positively correlated with local cell density. Here we present an effective approach to modulate this group behaviour using multivalent peptide-polymer conjugates. Our results show that by attaching multiple AIP-4′ units to macromolecular scaffolds, the agr QS response in S. aureus was affected strongly, while displaying a clear multivalency effect.

Enzymatic optical resolution of norbornanecarboxylic esters using Pig Liver Esterase

The hydrolysis of a series of norbornane-type carboxylic esters catalyzed by pig liver esterase (PLE) has been investigated.It was found that an exo-ester function (syn to the C7 methylene group) is hydrolyzed with high preference.Enantioselective hydrolysis can be accomplished when a vicinal carbonyl-containing function (ester, formyl, acetyl) is present in a trans position with respect to the exo ester.The regiospecifity of the enzymatic hydrolysis has been used for the separation of exo/endo mixtures of the cycloadducts derived from cyclopentadiene and alkene esters.The regiospecifity and enantioselectivity of the enzymatic hydrolysis of norbornane-type esters were analyzed in terms of Tamm's substrate model and also by Griengl's method.