77336-38-0Relevant academic research and scientific papers
Cu-Catalyzed solvent-free, pot-economic synthesis of 1,3-dynes from 1,1-dibromoalkenes in the presence of DBU?H2O
Moodapelly, Shiva Krishna,Nanaji, Yerramsetti,Sharma, Gangavaram V.M.,Suneeel, Kanaparthy,Doddi, Venkata Ramana
, (2021/05/27)
An efficient synthesis of 1,3-diynes directly from 1,1-dibromoalkenes has been achieved by utilizing hydrated 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU.H2O) as a sole reagent and a catalyst CuI. In general, 1,3-diynes were synthesized from corresponding terminal alkynes, which in turn were obtained from 1,1-dibromoalkenes. The DBU.H2O allowed the synthesis of 1,3-diynes not only in a pot-efficient manner but also under solvent-free conditions at ambient temperature. A plausible mechanism is proposed via 1-bromoalkynes intermediate instead of terminal alkynes.
Natural Benzofurans. Synthesis of Medicagol Methoxybenzofuran
Scannell, Ralph T.,Stevenson, Robert
, p. 1727 - 1728 (2007/10/02)
A general route to 2-arylbenzofurans, consisting of reaction of an o-halogenophenol ester with a cuprous arylacetylide, was employed to synthesize medicagol methoxybenzofuran. 2,4-Dimethoxyacetophenone was converted to 2,4-dimethoxyphenylacetylene in thre
