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4-Nitro-2-trifluoromethylacetophenone is a chemical compound characterized by the molecular formula C10H6F3NO3. It is a yellow crystalline solid that serves as a crucial intermediate in the synthesis of various pharmaceuticals and agrochemicals. 4-Nitro-2-trifluoromethylacetophenone is known for its high melting point of 142-144°C and its solubility profile, being sparingly soluble in water but readily soluble in organic solvents such as ethanol and acetone. Due to its toxic and harmful nature upon ingestion, inhalation, or contact with skin or eyes, it is essential to handle 4-Nitro-2-trifluoromethylacetophenone with appropriate safety measures and protective equipment.

77344-68-4

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77344-68-4 Usage

Uses

Used in Pharmaceutical Industry:
4-Nitro-2-trifluoromethylacetophenone is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Nitro-2-trifluoromethylacetophenone is utilized as an intermediate for the production of pesticides and other agrochemicals. Its chemical properties make it suitable for the creation of effective and targeted pest control solutions.
Used in Organic Synthesis:
4-Nitro-2-trifluoromethylacetophenone is employed as a versatile building block in organic synthesis, enabling the creation of a wide range of organic compounds for various applications, including specialty chemicals and materials.
Used in Research and Development:
4-Nitro-2-trifluoromethylacetophenone is also used in research and development settings to explore its chemical properties and potential applications in new areas of chemistry and material science. Its unique structure and reactivity make it an interesting subject for scientific investigation.

Check Digit Verification of cas no

The CAS Registry Mumber 77344-68-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,4 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77344-68:
(7*7)+(6*7)+(5*3)+(4*4)+(3*4)+(2*6)+(1*8)=154
154 % 10 = 4
So 77344-68-4 is a valid CAS Registry Number.

77344-68-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Methyl-4-nitrophenyl)ethanone

1.2 Other means of identification

Product number -
Other names 1-(2-methyl-4-nitrophenyl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77344-68-4 SDS

77344-68-4Upstream product

77344-68-4Relevant academic research and scientific papers

2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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Page 24, (2010/02/08)

Selected 2-arylacetic acids, their derivatives and pharmaceutical compositions that contain these compounds are useful in inhibiting chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. In particular, 2(ortho)-substituted arylacetic acids or their derivatives, such as amides and sulfonamides, lack cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrophil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion.

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