77355-01-2Relevant academic research and scientific papers
Polyethylene glycol-bonded triethylammonium l-prolinate: A new biodegradable amino-acid-based ionic liquid for the one-pot synthesis of bis(pyrazolyl)methanes as DNA binding agents
Kordnezhadian, Reza,Shekouhy, Mohsen,Karimian, Somaye,Tavaf, Zohreh,Malek-Hosseini, Saeed,Shahsavani, Mohammad Bagher,Amirghofran, Zahra,Yousefi, Reza,Khalafi-Nezhad, Ali
, p. 16995 - 17012 (2020/11/02)
Polyethylene glycol-bonded triethylammonium l-prolinate ([PEG-TEA]LP) was prepared as a new, highly efficient, reusable and biodegradable amino-acid-based ionic liquid catalyst using cheap and easily accessible starting materials. The [PEG-TEA]LP chemical
Prospective new amidinothiazoles as leukotriene B4 inhibitors
Aly, Ashraf A.,Ibrahim, Mahmoud A.A.,El-Sheref, Essmat M.,Hassan, Alaa M.A.,Brown, Alan B.
, p. 414 - 427 (2018/09/18)
An efficient and one-step synthesis of the versatile, hitherto new derivatives resembling LY293111, a prospective potent antagonist of the leukotriene B4 (LTB4) receptor, were reported. The strategy was based on the synthesis of an amidinothiazole ring, c
Design, two-directional synthesis, DFT study of new pyrimido[5,4-d]pyrimidine-2,8-dione derivatives
Sheykhi-Estalkhjani, Ammar,Mahmoodi, Nosrat O.,Yahyazadeh, Asieh,Pasandideh Nadamani, Meysam,Taherpour Nahzomi, Hossein
, p. 749 - 756 (2019/01/08)
A facile two-directional synthesis of new pyrimido[5,4-d]pyrimidine-2,8-dione was reported via an efficient reaction of premade bis-aldehydes and 1-(2-amino-1,2-dicyanovinyl)-3-phenylurea in the presence of triethylamine as the base and Cu (II) as catalys
Synthesis, Molecular Docking Studies, and Anticonvulsant Evaluation of Novel bis-Phenylhydrazones against Chemically induced Seizures in Mice
Siddiqi, Humaira Masood,Tabasum, Aneela,Qasim, Sumera,Akhtar, Muhammad Shoaib,Kalsoom, Saima,Ansari, Farzana Latif
, p. 940 - 952 (2017/09/01)
A series of novel bis-phenylhydrazones were synthesized by the condensation of dialdehydes with phenylhydrazine to evaluate them for their anticonvulsant activity. Efficacy of newly synthesized compounds against pentylenetetrazole (PTZ)-induced, strychnin
Synthesis and mesomorphic properties of new methylene-linked linear symmetrical liquid crystal dimers
Al-Hamdani, Uhood J.,Al-Ibrahim, Aiman G.,Abbo, Hanna S.,Titinchi, Salam J.J.
, p. 13 - 22 (2015/03/14)
A series of methylene-linked symmetrical liquid crystal dimers were synthesized. Their structures were confirmed by physicochemical techniques. Differential scanning calorimetry and polarizing optical microscopy verified the liquid crystal behaviors and t
One-pot synthesis of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols and evaluation of their antimicrobial activity
Linga Goud,Ramesh,Ashok,Prabhakar Reddy
, p. 673 - 678 (2015/05/05)
Abstract A new series of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols were synthesized by reaction of bis(formylphenyl)glycols with benzil/benzoin and ammonium acetate in presence of iodine/acetic acid in ethanol. All newly synthesized compounds were char
Organocatalyzed step-growth polymerization through desymmetrization of cyclic anhydrides: Synthesis of chiral polyesters
Martin, Anthony,Robert, Frédéric,Taton, Daniel,Cramail, Henri,Vincent, Jean-Marc,Landais, Yannick
supporting information, p. 11946 - 11953 (2014/11/07)
The polymerization of prochiral bis-anhydrides with diols catalyzed by a cinchona alkaloid was shown to provide chiral polyesters in good yields and with high levels of stereocontrol. The structures of the polyesters were determined by 1H and
Visible-light-promoted synthesis of benzimidazoles
Park, Sehyun,Jung, Jaehun,Cho, Eun Jin
, p. 4148 - 4154 (2014/07/08)
A simple and environmentally-friendly synthetic method for benzimidazoles, which are important structural motifs in many applications owing to their various biological functions, has been developed. The reaction of o-phenylenediamine and a variety of aliphatic/aromatic aldehydes in methanol proceeds at room temperature with only natural sources, molecular oxygen and visible light. A simple and eco-friendly synthetic method for benzimidazoles, which are important structural motifs in many applications owing to their various biological functions, has been developed. The reaction of o-phenylenediamine and a variety of aliphatic/aromatic aldehydes in methanol proceeds at room temperature with only natural sources, molecular oxygen and visible light. Copyright
A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents
Tyagi, Vikas,Khan, Shahnawaz,Shivahare, Rahul,Srivastava, Khushboo,Gupta, Suman,Kidwai, Saqib,Srivastava, Kumkum,Puri,Chauhan, Prem M.S.
supporting information, p. 291 - 296 (2013/02/23)
A natural product inspired molecular hybridization approach led us to a series of novel pentamidine based pyrimidine and chalcone scaffolds. All the hybrids were evaluated for their anti-leishmanial potential. Most of the screened compounds have showed significant in vitro anti-leishmanial activity with less cytotoxicity in comparison to the standard drugs (pentamidine, sodium stibogluconate, and miltefosine). Additionally, anti-malarial screening of these compounds was also done and four compounds have shown superior activity against chloroquine resistance strain (K1) of Plasmodium falciparum.
New bispyrazoline derivatives built around aliphatic chains: Synthesis, characterization and antimicrobial studies
Yusuf, Mohamad,Jain, Payal
, p. 117 - 127 (2013/05/08)
The bispyrazolines 3a-3h built around the alkyl chains of varying lengths have been synthesized from the cyclization reactions of bischalcones with phenyl hydrazine. The bischalcones 2a-2h were obtained from the Claisen-Schmidt reactions of acetophenone w
