77372-73-7 Usage
Uses
Used in Pharmaceutical Industry:
6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE is used as a potential antimalarial agent for its ability to inhibit the growth of Plasmodium falciparum, the parasite responsible for malaria. It has shown promising results in some studies, indicating its potential for further development in this area.
Additionally, 6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE is used as a potential antitumor agent for its ability to inhibit the growth of certain cancer cells. Research has explored its antitumor properties, suggesting that it may have therapeutic applications in oncology.
Overall, 6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE shows promise for further development as a pharmaceutical compound with important therapeutic applications in both antimalarial and antitumor treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 77372-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,7 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 77372-73:
(7*7)+(6*7)+(5*3)+(4*7)+(3*2)+(2*7)+(1*3)=157
157 % 10 = 7
So 77372-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N4O2.C4H4O4/c18-17(19)11-2-3-12-10(9-11)1-4-13(15-12)16-7-5-14-6-8-16;5-3(6)1-2-4(7)8/h1-4,9,14H,5-8H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
77372-73-7Relevant academic research and scientific papers
, p. 695 - 706 (2013)
Twelve alkyl analogues (1-12) of the high-affinity serotonin transporter (SERT) inhibitor 6-nitroquipazine (6-NQ) were synthesized and studied using in vitro radioligand competition binding assays to determine their binding affinity (Ki). The p
A new efficient synthesis of 6-nitroquipazine
Lee, Byoung Se,Lee, Byung Chul,Jun, Jong-Gab,Chi, Dae Yoon
, p. 2637 - 2641 (2007/10/03)
A convenient and regioselective synthesis of 6-nitroquipazine from hydrocarbostyril in three steps is described. This synthetic route involved a nitration, a chlorination followed by aromatization, and an aromatic substitution reaction.
