77372-73-7 Usage
General Description
6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE is a chemical compound with a molecular formula C14H15N5O2. It is a nitro-substituted quinoline derivative that contains a piperazine moiety. 6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE has been studied for its potential pharmacological properties, including its antimalarial and antitumor activities. It has been investigated for its ability to inhibit the growth of Plasmodium falciparum, the parasite responsible for malaria, and has shown promising results in some studies. Additionally, its antitumor properties have also been explored, with research indicating its potential to inhibit the growth of certain cancer cells. Overall, 6-NITRO-2-PIPERAZIN-1-YL-QUINOLINE shows potential for further development as a pharmaceutical compound with important therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 77372-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,7 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 77372-73:
(7*7)+(6*7)+(5*3)+(4*7)+(3*2)+(2*7)+(1*3)=157
157 % 10 = 7
So 77372-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N4O2.C4H4O4/c18-17(19)11-2-3-12-10(9-11)1-4-13(15-12)16-7-5-14-6-8-16;5-3(6)1-2-4(7)8/h1-4,9,14H,5-8H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
77372-73-7Relevant articles and documents
Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors
, p. 695 - 706 (2013)
Twelve alkyl analogues (1-12) of the high-affinity serotonin transporter (SERT) inhibitor 6-nitroquipazine (6-NQ) were synthesized and studied using in vitro radioligand competition binding assays to determine their binding affinity (Ki). The p