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"Z-Cys(Bzl)-Gly2-Cys(Bzl)-Gly2-NHCH2CH2-SBzl" is a complex peptide-like molecule with a unique structure. It features a backbone of alternating glycine (Gly) residues, which are the simplest amino acids. The molecule includes cysteine (Cys) residues, which are notable for their thiol side chains that can form disulfide bonds, crucial for protein stability and structure. The cysteine residues in this molecule are protected with benzyl (Bzl) groups, which prevent unwanted side reactions, a common practice in peptide synthesis to control reactivity. The molecule also contains a terminal benzylthiol (SBzl) group, which could be used for further chemical modifications or as a protecting group. The "Z" prefix indicates the presence of a carbobenzyloxy (Cbz) group, a common amino-terminal protecting group in peptide synthesis. This molecule is likely used in the synthesis of larger peptides or proteins, where the controlled release of the cysteine residues' thiol groups is necessary for the formation of specific disulfide bonds, which are essential for the correct folding and function of many proteins.

77374-86-8

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77374-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77374-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,7 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 77374-86:
(7*7)+(6*7)+(5*3)+(4*7)+(3*4)+(2*8)+(1*6)=168
168 % 10 = 8
So 77374-86-8 is a valid CAS Registry Number.

77374-86-8Relevant academic research and scientific papers

Studies Relating to the Ferredoxins. Part 3. The Synthesis of Some Cysteine-Glycine Peptides for Iron-Sulphur Complexing Studies

Balasubramaniam, Ambikaipakan,Burt, Roger J.,Christou, George,Ridge, Brian,Rydon, H. N.

, p. 310 - 317 (2007/10/02)

Three peptides with the general structure Ac-Gly2.(Cys.Glym)n.Cys.Gly3.Cys.Gly2.NH2 (1; m = 2 or 3; n = 0 or 1), four with the general structure Ac.Gly2.Cysn.Gly2.NH2

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