77377-79-8

Upstream product

• 71624-37-8 1,2-epimino-2-deoxy-2-epi-fortimicin B 
• 78027-24-4 2-chloro-2-deoxyfortimicin B 
• 75315-63-8 N-(benzyloxycarbonyl)succinimide 
• 71624-35-6 1,2',6'-tri-N-benzyloxycarbonyl-2-O-(methylsulfonyl)fortimicin B 
• 2899-60-7 Cbz-Gly-ONSuc 
• 78043-71-7 1,2',6',2''-tetra-N-benzyloxycarbonyl-2-O-(methylsulfonyl)fortimicin A 

Downstream Products

• 77377-84-5 2-chloro-2-deoxy-2-epi-fortimicin A 
• 78043-72-8 1,2',6'-tri-N-benzyloxycarbonyl-2-chloro-2-deoxy-2-epi-fortimicin B 
• 78027-24-4 2-chloro-2-deoxy-2-epi-fortimicin B 

Relevant academic research and scientific papers

2-SUBSTITUTED FORTIMICINS BY RING OPENING OF 2-DEOXY-1,2-EPIMINO-2-EPI-FORTIMICIN B AND BY NUCLEOPHILIC DISPLACEMENTS OF 2-O-(METHYLSULFONYL)FORTIMICIN DERIVATIVES

Opening of the aziridine ring of 2-deoxy-1,2-epimino-2-epi-fortimicin B (10) has been effected with both chloride and azide.The reactions are both stereo- and regiospecific and give 2-chloro-2-deoxyfortimicin B (2c) and 2-azido-2-deoxyfortimicin B (2d).Th