77381-62-5

Upstream product

• 51816-11-6 N-(2-chloro-ethyl)-2-phenoxy-acetamide 
• 194935-57-4 N-(2-bromoethyl)-2-phenoxyacetamide 

Downstream Products

• 77396-87-3 bis-[2-(phenoxyacetyl-amino)-ethyl]-disulfide 
• 77396-86-2 {(3S,4R)-3-(1-Hydroxy-ethyl)-2-oxo-4-[2-(2-phenoxy-acetylamino)-ethylsulfanylcarbonylmethyl]-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 77396-85-1 3-Hydroxy-5-{2-hydroxy-1-[2-(2-phenoxy-acetylamino)-ethylsulfanylcarbonyl]-propyl}-1H-pyrrole-2-carboxylic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Thionation of N-(ω-halogenoalkyl)-substituted amides with Lawesson's reagent: Facile synthesis of 4,5-dihydro-1,3-thiazoles and 5,6-dihydro-4H-1,3- thiazines

The thionation and cyclization of N-(ω-halogenoalkyl)-substituted amides (and related compounds) with Lawesson's reagent (LR = 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide) has been investigated. Treatment of the amides 1 with LR gav