773871-77-5 Usage
Uses
Used in Pharmaceutical Research and Development:
(4'-TRIFLUOROMETHYL-BIPHENYL-2-YL)-METHANOL is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, including the trifluoromethyl group and methanol group, allows for the development of new drugs with potentially improved properties, such as enhanced solubility, stability, and bioavailability.
Used in Chemical Research:
In the field of chemical research, (4'-TRIFLUOROMETHYL-BIPHENYL-2-YL)-METHANOL serves as a valuable compound for studying the effects of structural modifications on the properties and reactivity of biphenyl derivatives. This can lead to a better understanding of the underlying chemistry and the development of novel applications in various industries.
Used in Drug Discovery:
(4'-TRIFLUOROMETHYL-BIPHENYL-2-YL)-METHANOL is used as a lead compound in drug discovery, where its unique structural features can be exploited to design and develop new therapeutic agents. The trifluoromethyl group may impart specific biological activities, while the methanol group could enhance the compound's pharmacokinetic profile, making it a promising starting point for the development of innovative drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 773871-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,3,8,7 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 773871-77:
(8*7)+(7*7)+(6*3)+(5*8)+(4*7)+(3*1)+(2*7)+(1*7)=215
215 % 10 = 5
So 773871-77-5 is a valid CAS Registry Number.
773871-77-5Relevant academic research and scientific papers
A novel 4-aminoantipyrine-Pd(II) complex catalyzes Suzuki-Miyaura cross-coupling reactions of aryl halides
Contreras-Celedn, Claudia A.,Mendoza-Rayo, Daro,Rincn-Medina, Jos A.,Chacn-Garca, Luis
supporting information, p. 2821 - 2826 (2015/02/19)
A simple and efficient catalytic system based on a Pd complex of 4-aminoantipyrine, 4-AAP-Pd(II), was found to be highly active for Suzuki-Miyaura cross-coupling of aryl iodides and bromides with phenylboronic acids under mild reaction conditions. Good to excellent product yields from the cross-coupling reaction can be achieved when the reaction is carried out in ethanol, in the open air, using low loading of 4-AAP-Pd(II) as a precatalyst, and in the presence of aqueous K2CO3 as the base. A variety of functional groups are tolerated.
Highly efficient and versatile synthesis of polyarylfluorenes via Pd-catalyzed C-H bond activation
Hwang, Seung Jun,Kim, Hyun Jin,Chang, Sukbok
supporting information; experimental part, p. 4588 - 4591 (2009/12/09)
A facile protocol for the Pd-catalyzed preparative synthesis of fluorene derivatives has been developed. While a wide range of fluorenes were easily obtained with high efficiency and selectivity under mild conditions, excellent functional group tolerance
SUBSTITUTED 5-OXO PYRAZOLES AND [1,2,4]TRIAZOLES AS ANTIVIRAL AGENTS
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Page/Page column 38-39, (2008/06/13)
The present invention provides compounds of formula (I) wherein X and R1-R7 are as defined herein. Compositions containing these compounds, and methods for inhibiting HCV RNA-dependent RNA polymerase and treating hepatitis C and rela
