77412-26-1

Upstream product

• 77412-25-0 4,4'-dimethoxy-2'-methoxymethoxychalcone epoxide 
• 58544-83-5 1-[4-methoxy-2-(methoxymethoxy)phenyl]ethanone 
• 97080-68-7 (Z)-1-(4-Methoxy-2-methoxymethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone 
• 35095-72-8 (4-Methoxy-2-methoxymethoxy-phenyl)-[(2S,3R)-3-(4-methoxy-phenyl)-oxiranyl]-methanone 

Downstream Products

• 131121-47-6 (αR)-4,4'-dimethoxy-α-O-(4-methoxybenzoyl)-2'-O-methoxymethyldihydrochalcone 
• 131121-52-3 (αS)-4,4'-dimethoxy-α-O-(4-methoxybenzoyl)-2'-O-methoxymethyldihydrochalcone 

Relevant academic research and scientific papers

ENANTIOSELECTIVE SYNTHESIS OF FLAVONOIDS. PART 2. POLY-OXYGENATED α-HYDROXYDIHYDROCHALCONES AND CIRCULAR DICHROIC ASSESSMENT OF THEIR ABSOLUTE CONFIGURATION

Chiral chalcone epoxides exhibiting the oxygenation patterns of naturally occurring flavonoids and isoflavonoids were transformed into the corresponding α-hydroxydihydrochalcones.The availability of both enantiomers permitted assessment of the absolute co

A Novel α-Hydroxydihydrochalcone from the Heartwood of Pterocarpus angolensis D.C.: Absolute Configuration, Synthesis, Photochemical Transformations, and Conversion into α-Methyldeoxybenzoins

The absolute configuration of (αR)-α,2'-dihydroxy-4,4'-dimethoxydihydrochalcone from the heartwood of Pterocarpus angolensis D.C. is established.Its structure is substantiated by synthesis and by photochemical conversion of its α-O-tosyl derivative into an α-tosyloxymethyldeoxybenzoin and hence to the α-methyldeoxybenzoin analogue.The photochemical step also leads, amongst others, to α-hydroxymethyldeoxybenzoin, β-hydroxydihydrochalcone, and 2-benzylbenzofuran-3-one analogues depending on the conditions the photolysis.