77412-34-1Relevant academic research and scientific papers
Design, synthesis and biological activities of dihydroaurones
VENKATESWARLU, SOMEPALLI,MURTY, GANDROTU NARASIMHA,SATYANARAYANA, MEKA,SIDDAIAH, VIDAVALUR
, p. 1396 - 1402 (2021/06/09)
To widen aurones applicability in achromatic food and cosmetic applications, a series of dihydroaurones were designed to mimic natural aurones as well as synthetic aurones. Dihydroaurones have been synthesized from the corresponding aurones by hydrogenation. These dihydroaurones and their corresponding aurones were screened for antioxidant, anti-inflammatory and tyrosinase enzyme inhibitory activity. Synthesized dihydroaurones (3b-f) displayed superior antioxidant activity in superoxide free radical scavenging assay than the standard gallic acid. Dihydroaurones (3b-f) also exhibited significant tyrosinase enzyme inhibitory activity and two dihydroaurones (3h, 3j) showed promising 5-lipoxygenase inhibitory activity.
A Novel α-Hydroxydihydrochalcone from the Heartwood of Pterocarpus angolensis D.C.: Absolute Configuration, Synthesis, Photochemical Transformations, and Conversion into α-Methyldeoxybenzoins
Bezuidenhoudt, Barend C. B.,Brandt, E. Vincent,Roux, David G.
, p. 263 - 269 (2007/10/02)
The absolute configuration of (αR)-α,2'-dihydroxy-4,4'-dimethoxydihydrochalcone from the heartwood of Pterocarpus angolensis D.C. is established.Its structure is substantiated by synthesis and by photochemical conversion of its α-O-tosyl derivative into an α-tosyloxymethyldeoxybenzoin and hence to the α-methyldeoxybenzoin analogue.The photochemical step also leads, amongst others, to α-hydroxymethyldeoxybenzoin, β-hydroxydihydrochalcone, and 2-benzylbenzofuran-3-one analogues depending on the conditions the photolysis.
