77415-61-3Relevant academic research and scientific papers
SYNTHESIS AND ABSOLUTE CONFIGURATION OF THREE ISOMERIC SPIRO-BIS(2-PYRROLIDINONES)
Kajtar, Marton,Hollosi, Miklos,Kinsky, Klaus,Majer, Zsuzsanna
, p. 936 - 949 (2007/10/02)
Syntheses are described for three isomeric spiro-bis-(2-pyrrolidinones): 2,7-diazaspirononane-3,8-dione (II), 2,7-diazaspirononane-1,8-dione (IV) and 1,7-diazaspirononane-2,8-dione (VI).All the syntheses were carried out starting from 3-carboxy-5-oxo-3-pyrrolidineacetic acid (VIII) of known configuration, allowing the assignation of absolute configuration to compounds II, IV and VI synthetized through stereochemically unequivocal reaction steps.
