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774218-70-1

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774218-70-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 774218-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,4,2,1 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 774218-70:
(8*7)+(7*7)+(6*4)+(5*2)+(4*1)+(3*8)+(2*7)+(1*0)=181
181 % 10 = 1
So 774218-70-1 is a valid CAS Registry Number.

774218-70-1Relevant articles and documents

SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa

Smallheer, Joanne M.,Alexander, Richard S.,Wang, Jianmin,Wang, Shuaige,Nakajima, Suanne,Rossi, Karen A.,Smallwood, Angela,Barbera, Frank,Burdick, Debra,Luettgen, Joseph M.,Knabb, Robert M.,Wexler, Ruth R.,Jadhav, Prabhakar K.

, p. 5263 - 5267 (2007/10/03)

An X-ray crystal structure of compound 3b complexed to fIXa shows a similar binding mode to that previously observed with pyrazole inhibitors in the fXa active site. The best combination of fIXa potency and selectivity in this series was obtained with 5-c

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