77433-13-7Relevant academic research and scientific papers
Cyclization process for producing aziridine-2-carboxylic acid or its salts
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, (2008/06/13)
A process for producing aziridine-2-carboxylic acid or its salts is provided which comprises treating an alpha-halogeno-beta-aminopropionitrile or its mineral acid salt with an alkali or alkaline earth metal hydroxide in water or in a water-containing organic solvent. In a preferred embodiment, aziridine-2-carboxylic acid or its salt is produced by treating the reaction mixture containing an alpha-halogeno-beta-aminopropionitrile obtained by reacting an alpha, beta-dihalogenopropionitrile or an alpha-halogenoacrylonitrile with ammonia, with an alkali or alkaline earth metal hydroxide in the presence of water without isolating the alpha-halogeno-beta-aminopropionitrile from the reaction mixture beforehand.
Alpha-halogeno-beta-aminopropionitriles or the mineral acid salts thereof, and processes for production thereof
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, (2008/06/13)
A process for producing an alpha-halogeno-beta-aminopropionitrile which comprises reacting an alpha,beta-dihalogenopropionitrile with ammonia in water and/or an organic solvent. Action of a mineral acid on the reaction product gives a mineral acid salt of an alpha-halogeno-beta-aminopropionitrile. An isolated alpha-halogeno-beta-aminopropionitrile and a sulfate thereof are also provided.
