77434-05-0

Upstream product

• 2812-46-6 proline tert-butyl ester 
• 77434-01-6 Z-(CmOH)-L-Val-OEt 
• 5366-33-6 H-L-Val-OEt*TosOH 
• 77328-37-1 ethyl N-carboxymethyl-L-valinate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 77434-19-6 (S)-1-{2-[Benzyloxycarbonyl-((S)-1-carboxy-2-methyl-propyl)-amino]-acetyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 100689-97-2 H-L-Phe-Cm(L-Pro-O-t-Bu)-L-Val-OEt 
• 100689-96-1 Z-L-Phe-Cm(L-Pro-O-t-Bu)-L-Val-OEt 
• 100689-98-3 (S)-1-{2-[[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-phenyl-propionyl]-((S)-1-ethoxycarbonyl-2-methyl-propyl)-amino]-acetyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Studies of Unusual Amino Acids and Their Peptides. XIII. The Chemistry of N-(Carboxymethyl)amino Acids. II. The Synthesis of Peptides Containing N-(Carboxymethyl)amino Acids

The basic problems in the synthesis of peptides with N-carboxymethyl(Cm-)amino acids were investigated.Several kinds of N-protected derivatives of a free Cm-amino acid and the N-benzyloxycarbonyl (Z) derivative of its monoester were obtained by the conven