77437-65-1

Upstream product

• 4779-31-1 Z-Asp-OBn 
• 77437-63-9 (3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxymethyl]-tetrahydro-pyran-2-ylamine 
• 127570-61-0 2,3,4-tri-O-benzyl-N-(benzyl N-benzyloxycarbonyl-L-β-aspartyl)-α-D-glucopyranosylamine 
• 95084-13-2 phenylthio-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1→6)-2,3,4-tri-O-benzyl-β-D-glucopyranoside 

Downstream Products

• 77437-53-7 O-(α-D-glucopyranosyl)-(1<*>6)-O-β-D-glucopyranosyl-(1<*>6)-N-(L-β-aspartyl)-α-D-glucopyranosylamine 

Relevant academic research and scientific papers

An Efficient and Stereocontrolled Synthesis of the Nephritogenoside Core Structure

An efficient and stereocontrolled synthesis of the core trisaccharide 2 of nephritogenic glycopeptide, nephritogenoside 1 is described.Key to our synthetic strategy was β-selective glycosylation without neighboring group participation. Key words: nephrito

Synthetic Studies on Nephritogenic Glycosides. Synthesis of α-Glc-(1->6)-β-Glc-(1->6)-α-Glc-(1->Asn)

Glucotriosyl asparagine 2, a proposed structure for the glycan part of nephritogenic glucopeptide 1 isolated from the glomerular basement-membrane of rat, was synthesized in regio- and stereo-selective manners starting from α-D-glycopyranosyl azide 8.The key intermediate for this synthesis was designed to be glucotriosyl azide 21, based on retrosynthetic considerations.