774556-83-1 Usage
Uses
Used in Pharmaceutical Industry:
(4-FLUOROBENZYL)(2-PYRIDINYLMETHYL)AMINE HYDROCHLORIDE is used as an intermediate compound for the synthesis of medications. Its unique structure allows it to be a valuable building block in the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Research and Development:
In the research and development sector, (4-FLUOROBENZYL)(2-PYRIDINYLMETHYL)AMINE HYDROCHLORIDE is used as a subject of study for understanding chemical reactivity and biological activity. Its distinct chemical composition makes it an interesting candidate for exploring various reactions and interactions with other molecules, which can lead to advancements in chemical and biological sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 774556-83-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,4,5,5 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 774556-83:
(8*7)+(7*7)+(6*4)+(5*5)+(4*5)+(3*6)+(2*8)+(1*3)=211
211 % 10 = 1
So 774556-83-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H13FN2/c14-12-6-4-11(5-7-12)9-15-10-13-3-1-2-8-16-13/h1-8,15H,9-10H2
774556-83-1Relevant academic research and scientific papers
Low-Molecular-Weight CXCR4 Ligands with Variable Spacers
Narumi, Tetsuo,Aikawa, Haruo,Tanaka, Tomohiro,Hashimoto, Chie,Ohashi, Nami,Nomura, Wataru,Kobayakawa, Takuya,Takano, Hikaru,Hirota, Yuki,Murakami, Tsutomu,Yamamoto, Naoki,Tamamura, Hirokazu
, p. 118 - 124 (2013/02/26)
Low-molecular-weight CXCR4 ligands based on known lead compounds including the 14-mer peptide T140, the cyclic pentapeptide FC131, peptide mimetics, and dipicolylamine-containing compounds were designed and synthesized. Three types of aromatic spacers, 1,4-phenylenedimethanamine, naphthalene-2,6-diyldimethanamine, and [1,1′-biphenyl]-4,4′-diyldimethanamine, were used to build four pharmacophore groups. As pharmacophore groups, 2-pyridylmethyl and 1-naphthylmethyl are present in all of the compounds, and several aromatic groups and a cationic group from 1-propylguanidine and 1,1,3,3-tetramethyl-2-propylguanidine were also used. Several compounds showed significant CXCR4 binding affinity, and zinc(II) complexation of bis(pyridin-2-ylmethyl)amine moieties resulted in a remarkable increase in CXCR4 binding affinity.
