77456-14-5 Usage
Uses
Used in Oncology:
(-)-1,1'-Dithiodiethylenebis[3-(2-chloroethyl)-3-nitrosourea] is used as an anticancer agent for the treatment of various forms of cancer. Its ability to inhibit cancer cell growth by damaging their DNA makes it a valuable tool in oncology. (-)-1,1'-Dithiodiethylenebis[3-(2-chloroethyl)-3-nitrosourea] is especially useful in treating brain tumors due to its capacity to cross the blood-brain barrier, offering a therapeutic option for patients with such conditions.
Used in Cancer Research:
In addition to its clinical applications, (-)-1,1'-Dithiodiethylenebis[3-(2-chloroethyl)-3-nitrosourea] is also utilized in cancer research to study the mechanisms of action of nitrosourea compounds and their effects on different types of cancer cells. This research can contribute to the development of new and more effective cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 77456-14-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,5 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 77456-14:
(7*7)+(6*7)+(5*4)+(4*5)+(3*6)+(2*1)+(1*4)=155
155 % 10 = 5
So 77456-14-5 is a valid CAS Registry Number.
77456-14-5Relevant academic research and scientific papers
New oncostatic nitrosourea of clinical interest. I. Synthesis and identification of CNCC
Oiry,Imbach
, p. 305 - 309 (2007/10/02)
This paper describes CNCC synthesis, a mixture of the three nitrosourea isomer corresponding to cystamine as the starting compound. The regioselective synthesis of one of these isomeric products is described and the structure of this compound is determined by the usual analytical approaches: NMR, HPLC.
New oncostatic nitrosourea of clinical interest. II. Study of CNCC constituents
Oiry,Pompon,Madelmont,Imbach
, p. 311 - 314 (2007/10/02)
CNCC is an isomeric mixture of dinitrosated chloroethyl nitrosoureas. Two of these being identified, a complete analysis of the isolated mixture obtained through nitrosation of the urea corresponding to cystamine is then possible. Furthermore, a new synth
